Eagan Marianne S, Lyle Roseann M, Gunther Carolyn W, Peacock Munro, Teegarden Dorothy
Department of Foods and Nutrition, Purdue University, 1264 Stone Hall, 700 West State Street, West Lafayette, IN 47907, USA.
Obesity (Silver Spring). 2006 Dec;14(12):2242-8. doi: 10.1038/oby.2006.263.
Previous results from this laboratory suggest that a 1-year dairy intake intervention in young women does not alter fat mass. The objective of this study was to determine the impact of the 1-year dairy intervention 6 months after completion of the intervention.
Previously, normal-weight young women (n = 154) were randomized to one of three calcium intake groups: control (<800 mg/d), medium dairy (1000 to 1100 mg/d), or high dairy (1300 to 1400 mg/d) for a 1-year trial (n = 135 completed). In the current study, 51 women were assessed 6 months after completion of the intervention trial. Body compositions (body fat, lean mass) were measured using DXA. Self-report questionnaires were utilized to measure activity and dietary intake (kilocalories, calcium).
The high-dairy group (n = 19) maintained an elevated calcium intake (1027 +/- 380 mg/d) at 18 months compared with the control group (n = 18, 818 +/- 292; p = 0.02). Mean calcium intake over the 18 months predicted a negative change in fat mass (p = 0.04) when baseline BMI was controlled in regression analysis (model R(2) = 0.11). 25-Hydroxyvitamin D levels were correlated with fat mass at each time-point (baseline, r = -0.41, p = 0.003; 12 months, r = -0.42, p = 0.002; 18 months, r = -0.32, p = 0.02) but did not predict changes in fat mass.
Dietary calcium intake over 18 months predicted a negative change in body fat mass. Thus, increased dietary calcium intakes through dairy products may prevent fat mass accumulation in young, healthy, normal-weight women.
本实验室之前的研究结果表明，对年轻女性进行为期1年的乳制品摄入干预并不会改变脂肪量。本研究的目的是确定干预结束6个月后，为期1年的乳制品干预所产生的影响。
此前，体重正常的年轻女性（n = 154）被随机分为三个钙摄入量组之一：对照组（<800毫克/天）、中等乳制品组（1000至1100毫克/天）或高乳制品组（1300至1400毫克/天），进行为期1年的试验（n = 135人完成）。在本研究中，51名女性在干预试验结束6个月后接受了评估。使用双能X线吸收法测量身体成分（体脂肪、瘦体重）。采用自我报告问卷来测量活动量和饮食摄入量（千卡、钙）。
与对照组（n = 18，818 ± 292；p = 0.02）相比，高乳制品组（n = 19）在18个月时保持了较高的钙摄入量（1027 ± 380毫克/天）。在回归分析中控制基线体重指数时，18个月内的平均钙摄入量预测了脂肪量的负变化（p = 0.04）（模型R² = 0.11）。在每个时间点（基线，r = -0.41，p = 0.003；12个月，r = -0.42，p = 0.002；18个月，r = -0.32，p = 0.02），25-羟基维生素D水平与脂肪量相关，但不能预测脂肪量的变化。
18个月内的膳食钙摄入量预测了身体脂肪量的负变化。因此，通过乳制品增加膳食钙摄入量可能会防止年轻、健康、体重正常的女性脂肪量增加。
