Splieth Christian H, Sümnig Wolfgang, Bessel Frank, John Ulrich, Kocher Thomas
Center for Oral Health, University of Greifswald, Greifswald, Germany.
Quintessence Int. 2007 Jan;38(1):23-9.
The aim of this study was to assess the prevalence and intraoral distribution of oral mucosal lesions in a representative adult population (Study of Health in Pomerania/Germany).
The study sample comprised 6267 randomly selected subjects who were scheduled for examination from 1997 to 2001 (population-based cross-sectional study; response rate: 69%; age range 20 to 81 years).
The prevalence of oral mucosal lesions was age dependent (5.56% in 20- to 29-year-olds to 19.55% in 70- to 81-year-olds) with an overall prevalence of 11.83%. The prevalence in men (12.20%) was slightly higher than in women (11.40%). Exophytic neoplasia was the most prevalent alteration (3.00%), followed by leukoplakia simplex (prevalence 2.85%). Premalignant lesions were found in 0.57% of the participants, with lichen ruber mucosae contributing the major part (0.48%). Exophytic neoplasia was most often situated in the buccal mucosa, the hard palate, or the mucosa of the lower lip.
These data stress the importance of screening for oral mucosal lesions, especially because of a predicted increase in the number of elderly persons in industrialized countries.
本研究旨在评估德国波美拉尼亚健康研究中具有代表性的成年人群口腔黏膜病变的患病率及口腔内分布情况。
研究样本包括1997年至2001年随机选取的6267名受试者(基于人群的横断面研究;应答率:69%;年龄范围20至81岁)。
口腔黏膜病变的患病率与年龄相关(20至29岁人群中为5.56%,70至81岁人群中为19.55%),总体患病率为11.83%。男性患病率(12.20%)略高于女性(11.40%)。外生性肿瘤是最常见的病变(3.00%),其次是单纯性白斑(患病率2.85%)。0.57%的参与者发现有癌前病变,其中黏膜性苔藓占主要部分(0.48%)。外生性肿瘤最常位于颊黏膜、硬腭或下唇黏膜。
这些数据强调了筛查口腔黏膜病变的重要性,特别是考虑到工业化国家老年人数量预计会增加。