在39摄氏度的细胞培养中连续传代后，疱疹病毒萨米里对狨猴的毒力减弱。
Attenuation of herpesvirus saimiri for marmosets after successive passage in cell culture at 39 degrees C.
作者信息
Schaffer P A, Falk L A, Deinhardt F
出版信息
J Natl Cancer Inst. 1975 Nov;55(5):1243-6. doi: 10.1093/jnci/55.5.1243.
PMID:173864
Abstract
A variant of Herpesvirus saimiri (HVS) stably attenuated for marmosets was isolated after serial passage of wild-type HVS in cell culture at 39 degrees C. Marmosets previously inoculated with attenuated virus experienced a significant delay in the development of lymphoma when challenged with wild-type HVS.
摘要
在39摄氏度的细胞培养中对野生型赛米利疱疹病毒（HVS）进行连续传代后，分离出一种对狨猴稳定减毒的赛米利疱疹病毒变体。先前接种过减毒病毒的狨猴在用野生型HVS攻击时，淋巴瘤的发展出现了显著延迟。
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