Intrauterine insemination outperforms intracervical insemination in a randomized, controlled study with frozen, donor semen.
作者信息
Patton P E, Burry K A, Thurmond A, Novy M J, Wolf D P
机构信息
Department of Obstetrics and Gynecology, Oregon Health Sciences University, Portland.
出版信息
Fertil Steril. 1992 Mar;57(3):559-64. doi: 10.1016/s0015-0282(16)54900-0.
OBJECTIVE
To assess the efficacy of intrauterine insemination (IUI) in a donor insemination program.
DESIGN
Prospective randomized clinical trial.
SETTING
Donor insemination program.
PATIENTS, PARTICIPANTS: Women undergoing insemination were randomly assigned to receive either IUI or intracervical insemination for a maximum of six cycles.
INTERVENTIONS
None.
MAIN OUTCOME MEASURE(S): Cycle fecundity rates between the two routes were compared.
RESULTS
The monthly fecundity rate for intracervical insemination was 5.1% compared with 23% by IUI. By life table analysis, pregnancy rates for IUI were significantly higher than intracervical insemination (P = 0.02).
CONCLUSIONS
Intrauterine insemination with quarantined donor sperm is superior to intracervical insemination.
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