紫外线照射的1型和2型单纯疱疹病毒激活内源性小鼠C型病毒
Activation of an endogenous mouse type C virus by ultraviolet-irradiated herpes simplex virus types 1 and 2.
作者信息
Hampar B, Aaronson S A, Derge J G, Chakrabarty M, Showalter S D, Dunn C Y
出版信息
Proc Natl Acad Sci U S A. 1976 Feb;73(2):646-50. doi: 10.1073/pnas.73.2.646.
Abstract
Infection of BALB/c mouse cells with UV-irradiated herpes simplex virus (HSV) types 1 and 2 resulted in activation of a xenotropic type C virus detected by infectious center formation in permissive rat cells. The levels of type C virus activated by HSV were related to the UV dose and the multiplicity of infection used. The ability of HSV to activate type C virus was eliminated by heat-inactivation and by neutralization with specific antiserum against HSV, but was not affected by purification or treatment with DNase and RNase. Maximum levels of type C virus in the cells and medium were observed within 1 day after HSV infection, and the levels returned to control cell values within 3-4 days. The possible significance of these findings with respect to the putative oncogenic potential of HSV is discussed.
摘要
用紫外线照射的1型和2型单纯疱疹病毒（HSV）感染BALB/c小鼠细胞，导致一种嗜异性C型病毒被激活，该病毒可通过在允许性大鼠细胞中形成感染中心来检测。HSV激活的C型病毒水平与紫外线剂量和所用感染复数有关。HSV激活C型病毒的能力可通过热灭活和用抗HSV的特异性抗血清中和而消除，但不受纯化或用DNA酶和RNA酶处理的影响。在HSV感染后1天内观察到细胞和培养基中C型病毒的最高水平，并且在3-4天内这些水平恢复到对照细胞的值。讨论了这些发现关于HSV假定致癌潜力的可能意义。
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本文引用的文献
1
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2
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J Bacteriol. 1966 Oct;92(4):1133-40. doi: 10.1128/jb.92.4.1133-1140.1966.
3
Induction of murine C-type viruses from clonal lines of virus-free BALB-3T3 cells.从无病毒的BALB-3T3细胞克隆系中诱导出鼠C型病毒。
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4
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J Mol Biol. 1973 Oct 15;80(1):93-117. doi: 10.1016/0022-2836(73)90235-0.
5
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