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Transcriptional control mechanisms for the expression of type I collagen genes.

作者信息

de Crombrugghe B, Vuorio T, Karsenty G, Maity S, Rutheshouser E C, Goldberg H

机构信息

Department of Molecular Genetics, University of Texas, M D Anderson Cancer Center, Houston 77030.

出版信息

Ann Rheum Dis. 1991 Nov;50 Suppl 4(Suppl 4):872-6. doi: 10.1136/ard.50.suppl_4.872.

DOI:10.1136/ard.50.suppl_4.872
PMID:1750800
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1033323/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b0e/1033323/2de7814f5920/annrheumd00463-0039-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b0e/1033323/2de7814f5920/annrheumd00463-0039-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b0e/1033323/2de7814f5920/annrheumd00463-0039-a.jpg

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2
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Increased type I collagen mRNA levels in cultured scleroderma fibroblasts.培养的硬皮病成纤维细胞中I型胶原蛋白mRNA水平升高。
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本文引用的文献

1
Increased type I collagen mRNA levels in cultured scleroderma fibroblasts.培养的硬皮病成纤维细胞中I型胶原蛋白mRNA水平升高。
Biochim Biophys Acta. 1984 Feb 24;781(1-2):183-6. doi: 10.1016/0167-4781(84)90136-2.
2
Increased collagen synthesis by scleroderma skin fibroblasts in vitro: a possible defect in the regulation or activation of the scleroderma fibroblast.体外硬皮病皮肤成纤维细胞胶原合成增加：硬皮病成纤维细胞调节或激活方面可能存在的缺陷。
J Clin Invest. 1974 Oct;54(4):880-9. doi: 10.1172/JCI107827.
3
Activation of type I collagen genes in cultured scleroderma fibroblasts.
PRDM5 通过与 RNA 聚合酶 II 结合调节发育中的骨骼中的胶原基因转录。
PLoS Genet. 2012;8(5):e1002711. doi: 10.1371/journal.pgen.1002711. Epub 2012 May 10.
4
Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription.Atf4 通过激活 Ihh 转录来调节软骨细胞增殖和分化，从而在软骨内骨化过程中发挥作用。
Development. 2009 Dec;136(24):4143-53. doi: 10.1242/dev.043281. Epub 2009 Nov 11.
5
chk-YB-1b, a Y-box binding protein activates transcription from rat alpha1(I) procollagen gene promoter.chk-YB-1b，一种Y盒结合蛋白，可激活大鼠α1（I）前胶原基因启动子的转录。
Biochem J. 1998 Dec 1;336 ( Pt 2)(Pt 2):373-9. doi: 10.1042/bj3360373.
6
Cell-specific expression of alpha 1(I) collagen-hGH minigenes in transgenic mice.α1（I）型胶原-hGH 微型基因在转基因小鼠中的细胞特异性表达
J Cell Biol. 1994 May;125(3):695-704. doi: 10.1083/jcb.125.3.695.
培养的硬皮病成纤维细胞中I型胶原基因的激活
J Cell Biochem. 1985;28(2):105-13. doi: 10.1002/jcb.240280204.
4
Coordinated regulation of type I and type III collagen production and mRNA levels of pro alpha 1(I) and pro alpha 2(I) collagen in cultured morphea fibroblasts.培养的硬斑病成纤维细胞中I型和III型胶原蛋白产生以及I型前α1和前α2胶原蛋白mRNA水平的协调调节。
Arch Dermatol Res. 1987;279(3):154-60. doi: 10.1007/BF00413250.
5
Elevated pro alpha 2(I) collagen mRNA levels in cultured scleroderma fibroblasts result from an increased transcription rate of the corresponding gene.培养的硬皮病成纤维细胞中前α2（I）型胶原mRNA水平升高是相应基因转录速率增加所致。
FEBS Lett. 1987 May 11;215(2):331-4. doi: 10.1016/0014-5793(87)80172-2.
6
Regulatory elements in the first intron contribute to transcriptional control of the human alpha 1(I) collagen gene.第一个内含子中的调控元件有助于人类α1（I）型胶原蛋白基因的转录控制。
Proc Natl Acad Sci U S A. 1987 Dec;84(24):8869-73. doi: 10.1073/pnas.84.24.8869.
7
Developmental and tissue-specific expression directed by the alpha 2 type I collagen promoter in transgenic mice.α2 I型胶原启动子在转基因小鼠中指导的发育和组织特异性表达。
Proc Natl Acad Sci U S A. 1986 Feb;83(3):725-9. doi: 10.1073/pnas.83.3.725.
8
Point mutations and small substitution mutations in three different upstream elements inhibit the activity of the mouse alpha 2(I) collagen promoter.
J Biol Chem. 1988 Sep 25;263(27):13909-15.
9
Selective activation of transcription by a novel CCAAT binding factor.
Science. 1988 Jul 29;241(4865):582-5. doi: 10.1126/science.3399893.
10
Identification of fibroblasts responsible for increased collagen production in localized scleroderma by in situ hybridization.通过原位杂交鉴定局限性硬皮病中负责胶原蛋白产生增加的成纤维细胞。
J Invest Dermatol. 1988 May;90(5):664-70. doi: 10.1111/1523-1747.ep12560826.