Joseph C, Hamilton G, O'Connor M, Nicholas S, Marshall R, Stanwell-Smith R, Sims R, Ndawula E, Casemore D, Gallagher P
PHLS Communicable Disease Surveillance Centre, London.
Epidemiol Infect. 1991 Dec;107(3):509-19. doi: 10.1017/s0950268800049207.
An outbreak of cryptosporidiosis occurred in the Isle of Thanet during December 1990 and January 1991. A total of 47 cases ranging in age from 2 months to 85 years were identified in residents from the Margate, Broadstairs and Ramsgate areas, with dates of onset of illness from 3 December to 14 January. A case-control study demonstrated a strong statistical association between illness and the consumption of unboiled tap water from a particular source, with evidence of a dose-response relationship. Although no cryptosporidial oocysts were identified in samples of untreated or treated water taken during the investigation, the results were consistent with the view that the source of infection was treated river water which was used to supplement borehole water.
1990年12月至1991年1月期间,萨尼特岛爆发了隐孢子虫病疫情。在马盖特、布罗德斯泰斯和拉姆斯盖特地区的居民中,共确诊了47例病例,年龄从2个月至85岁不等,发病日期为12月3日至1月14日。一项病例对照研究表明,患病与饮用来自特定水源的未煮沸自来水之间存在很强的统计学关联,并有剂量反应关系的证据。尽管在调查期间采集的未经处理或经过处理的水样中未发现隐孢子虫卵囊,但结果与感染源是用于补充井水的经处理河水这一观点一致。