Metcalf Amanda M
Department of Surgery, Roy J. and Lucille A. Carver College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.
Surg Clin North Am. 2007 Jun;87(3):633-41. doi: 10.1016/j.suc.2007.03.009.
Surgical therapy of ulcerative colitis is effective, safe, and provides an improved quality of life in those whose disease cannot be managed medically. In the elective setting, widespread acceptance of restorative proctocolectomy has made surgical therapy an attractive option in the overall management of ulcerative colitis. Enthusiasm for this procedure should be tempered by the acknowledgment of the significant incidence of pouchitis in the long term, however. Proctocolectomy with ileostomy remains a good surgical option for patients who are unsuitable for restorative procedures. The standard therapy for fulminant colitis or toxic megacolon remains subtotal colectomy with ileostomy. Patients undergoing subtotal colectomy are candidates for conversion to restorative procedures.
溃疡性结肠炎的手术治疗是有效、安全的,对于那些药物无法控制病情的患者,手术可改善其生活质量。在择期手术中,恢复性直肠结肠切除术被广泛接受,这使得手术治疗成为溃疡性结肠炎整体治疗中一个有吸引力的选择。然而,鉴于长期存在的显著的袋炎发生率,对该手术的热情应有所缓和。对于不适合恢复性手术的患者,直肠结肠切除加回肠造口术仍是一种不错的手术选择。暴发性结肠炎或中毒性巨结肠的标准治疗方法仍然是次全结肠切除加回肠造口术。接受次全结肠切除术的患者可考虑转为恢复性手术。