Park Yong Eun, Kim Tae Oh
Division of Gastroenterology, Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
World J Mens Health. 2020 Jul;38(3):285-297. doi: 10.5534/wjmh.190007. Epub 2019 Mar 22.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract that is usually diagnosed in young individuals. Crohn's disease and ulcerative colitis are the 2 principal forms of IBD. Patients with IBD demonstrate varying degrees of disease activity and sometimes need to undergo bowel surgery such as proctocolectomy with ileal pouch-anal anastomosis that involves removal of the entire colon and rectum with consequent sexual dysfunction. Several studies have shown that sulfasalazine, affects male fertility. Additionally, many men with IBD are unable to control their smoking, drinking, and eating habits, which can cause worsening of disease activity and fertility. Therefore, infertility and sexual dysfunction are important issues in young patients diagnosed with IBD because they are related to optimal management of the disease and patients' quality of life. Only a few studies have reported sexual dysfunction and infertility in men with IBD. Therefore, this study reviewed the current literature describing male sexual dysfunction scales and evaluated the causes of sexual dysfunction and infertility in men with IBD.
炎症性肠病(IBD)是一种胃肠道慢性炎症性疾病,通常在年轻人中被诊断出来。克罗恩病和溃疡性结肠炎是IBD的两种主要形式。IBD患者表现出不同程度的疾病活动,有时需要接受肠道手术,如回肠袋肛管吻合术的直肠结肠切除术,这涉及到整个结肠和直肠的切除,从而导致性功能障碍。几项研究表明,柳氮磺胺吡啶会影响男性生育能力。此外,许多患有IBD的男性无法控制他们的吸烟、饮酒和饮食习惯,这可能会导致疾病活动和生育能力恶化。因此,不孕和性功能障碍是诊断为IBD的年轻患者中的重要问题,因为它们与疾病的最佳管理和患者的生活质量有关。只有少数研究报道了IBD男性的性功能障碍和不孕情况。因此,本研究回顾了描述男性性功能障碍量表的当前文献,并评估了IBD男性性功能障碍和不孕的原因。