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在存在针对犬瘟热病毒的母源抗体的情况下对幼犬进行免疫接种。

Immunization of puppies in the presence of maternally derived antibodies against canine distemper virus.

作者信息

Pardo M C, Tanner P, Bauman J, Silver K, Fischer L

机构信息

Biological Research and Development, Merial Limited, Athens, Georgia, USA.

出版信息

J Comp Pathol. 2007 Jul;137 Suppl 1:S72-5. doi: 10.1016/j.jcpa.2007.04.015. Epub 2007 Jun 8.

DOI:10.1016/j.jcpa.2007.04.015
PMID:17560592
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7094307/
Abstract

Vaccination of dams with modified-live canine distemper virus (CDV) vaccines will elicit high concentrations of colostral antibody, that although vital for protection of the pup during the first weeks of life, can interfere with active vaccination against the virus. In the present study, 12 pups, 7-9 weeks of age, with maternally derived immunity to CDV, were vaccinated with a canarypox-vectored CDV vaccine. These pups were protected against intravenous challenge with CDV. Three littermate pups that were unvaccinated all developed clinical signs of infection after challenge, and two of these control pups died.

摘要

用改良活犬瘟热病毒（CDV）疫苗给母犬接种会引发高浓度的初乳抗体，虽然这对幼犬出生后的头几周至关重要，但可能会干扰针对该病毒的主动免疫接种。在本研究中，12只7至9周龄、具有母源CDV免疫力的幼犬接种了金丝雀痘载体CDV疫苗。这些幼犬在静脉注射CDV时受到了保护。三只未接种疫苗的同窝幼犬在接种后均出现了感染的临床症状，其中两只对照幼犬死亡。

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J Comp Pathol. 2007 Jul;137 Suppl 1:S72-5. doi: 10.1016/j.jcpa.2007.04.015. Epub 2007 Jun 8.
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本文引用的文献

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Vaccine. 2004 Sep 9;22(27-28):3642-8. doi: 10.1016/j.vaccine.2004.03.016.
2
Early DNA vaccination of puppies against canine distemper in the presence of maternally derived immunity.在存在母源免疫的情况下，对幼犬进行犬瘟热的早期DNA疫苗接种。
Vaccine. 2004 Jan 26;22(5-6):650-4. doi: 10.1016/j.vaccine.2003.08.022.
3
Vaccination of puppies with a lipid-formulated plasmid vaccine protects against a severe canine distemper virus challenge.用脂质体配方质粒疫苗对幼犬进行接种可抵御严重的犬瘟热病毒攻击。
Vaccine. 2003 Mar 7;21(11-12):1099-102. doi: 10.1016/s0264-410x(02)00608-4.
4
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Vaccine. 2002 Oct 4;20(29-30):3485-97. doi: 10.1016/s0264-410x(02)00344-4.
5
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6
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J Virol. 1997 Feb;71(2):1506-13. doi: 10.1128/JVI.71.2.1506-1513.1997.
7
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8
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9
Comparison between the immunizing effect in dogs and ferrets of living distemper vaccines, attenuated in dog tissue cultures and embryonated eggs.
Res Vet Sci. 1965 Oct;6(4):423-7.
10
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