Ribeiro Kátia Moreira Xavier, Alvez Janaína Maria, Pignatari Shirley S N, Weckx Luc Louis Maurice
Division of Pediatric Otolaryngology, Paulista School of Medicine, Federal University of São Paulo, SP, Brazil.
Braz J Infect Dis. 2006 Jun;10(3):165-8. doi: 10.1590/s1413-86702006000300002.
Human papilloma virus (HPV) is related to respiratory mucosal diseases, such as recurrent respiratory papillomatosis, as well as to upper-respiratory-tract malignancies. There are few reports concerning the prevalence of HPV in the upper respiratory tract of non-affected individuals. We examined the prevalence of HPV in the tonsils of children of the general population scheduled for tonsillectomy. Samples were taken from the tonsils of 100 children undergoing tonsillectomy and were then tested for HPV with the polymerase chain reaction (PCR) technique, utilizing the generic primers MY09 and MY 11. The study excluded children known to have HPV and HIV-related diseases. Parents and legal guardians completed a standardized socio-demographic questionnaire. The questionnaire revealed that 84% of the mothers had at least one risk factor for genital HPV. None of the tonsil samples were positive for HPV. Apparently HPV does not commonly colonize the tonsils of children undergoing routine tonsillectomy.
人乳头瘤病毒（HPV）与呼吸道黏膜疾病有关，如复发性呼吸道乳头状瘤病，也与上呼吸道恶性肿瘤有关。关于未受影响个体上呼吸道中HPV的流行情况，报告较少。我们检查了计划进行扁桃体切除术的普通人群中儿童扁桃体HPV的流行情况。从100名接受扁桃体切除术的儿童扁桃体中采集样本，然后使用通用引物MY09和MY11通过聚合酶链反应（PCR）技术检测HPV。该研究排除了已知患有HPV和HIV相关疾病的儿童。父母和法定监护人填写了标准化的社会人口统计学问卷。问卷显示，84%的母亲至少有一个生殖器HPV的风险因素。所有扁桃体样本HPV检测均为阴性。显然，HPV通常不会定植于接受常规扁桃体切除术儿童的扁桃体中。
