Tasdelen Fisgin Nuriye, Fisgin Tunc, Tanyel Esra, Doganci Levent, Tulek Necla, Guler Nil, Duru Feride
Department of Clinical Microbiology and Infectious Disease, Ondokuz Mayis University, Medical School, Samsun, Turkey.
Am J Hematol. 2008 Jan;83(1):73-6. doi: 10.1002/ajh.20969.
Three pediatric and two adult Turkish patients with Crimean Congo Hemorrhagic Fever (CCHF) induced hemophagocytic syndrome (HPS) were admitted to Ondokuz Mayis University Hospital, which is in the Middle Black Sea Region of Turkey. All of them had remarkable hemophagocytosis in the bone marrow with severe bleeding symptoms along with the other known clinical and laboratory findings of CCHF. We would like to present these patients and to discuss the pathophysiology and the effect of acquired HPS on the severity of the disease.
三名患有克里米亚-刚果出血热（CCHF）诱发噬血细胞综合征（HPS）的土耳其儿科患者和两名成年患者被收治到位于土耳其黑海中部地区的于尔杜兹马伊斯大学医院。他们所有人的骨髓中均有明显的噬血细胞现象，伴有严重出血症状以及CCHF的其他已知临床和实验室检查结果。我们希望介绍这些患者，并讨论获得性HPS的病理生理学及其对疾病严重程度的影响。
