Alfonsi Valeria, Montomoli Emanuele, Manini Ilaria, Alberini Isabella, Gentile Chiara, Rota Maria Cristina, Ciofi degli Atti Marta Luisa
Istituto Superiore di Sanità, National Center for Epidemiology Surveillance and Health Promotion, Italy.
Vaccine. 2007 Aug 10;25(32):6086-8. doi: 10.1016/j.vaccine.2007.05.019. Epub 2007 Jun 4.
We conducted a cross-sectional seroprevalence study of varicella-zoster virus (VZV) antibodies in childbearing age women aged 17-42 years. Sera were collected in Central Italy in years 2001-2002 and were tested by a commercial VZV IgG enzyme immunoassay. Overall VZV seroprevalence was 80.9% and it showed a significant increase by age, confirming a considerable circulation of VZV also in the older age groups not commonly considered at high risk. This study further supports the importance of vaccinating susceptible adolescents and women of childbearing age in order to reduce both maternal and foetal complications associated with varicella in pregnancy.
我们对17至42岁育龄妇女进行了一项水痘带状疱疹病毒（VZV）抗体的横断面血清流行率研究。2001年至2002年期间在意大利中部采集血清，并通过商用VZV IgG酶免疫测定法进行检测。总体VZV血清流行率为80.9%，且随年龄显著增加，这证实了VZV在通常不被视为高危的老年人群中也有相当程度的传播。这项研究进一步支持了为易感青少年和育龄妇女接种疫苗的重要性，以减少与孕期水痘相关的母婴并发症。
