• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Liposomal drug delivery. Advantages and limitations from a clinical pharmacokinetic and therapeutic perspective.

作者信息

Fielding R M

机构信息

Pharmacology/Toxicology Group, Liposome Technology, Inc., Menlo Park, California.

出版信息

Clin Pharmacokinet. 1991 Sep;21(3):155-64. doi: 10.2165/00003088-199121030-00001.

DOI:10.2165/00003088-199121030-00001
PMID:1764868
Abstract
摘要

相似文献

1
Liposomal drug delivery. Advantages and limitations from a clinical pharmacokinetic and therapeutic perspective.脂质体药物递送：从临床药代动力学和治疗学角度看其优势与局限性
Clin Pharmacokinet. 1991 Sep;21(3):155-64. doi: 10.2165/00003088-199121030-00001.
2
[Nanostructured liposomal systems as transport agents for anticancer drugs].[纳米结构脂质体系统作为抗癌药物的转运载体]
Vestn Ross Akad Med Nauk. 2012(3):23-31.
3
Pulmonary delivery of insulin by liposomal carriers.脂质体载体介导的胰岛素肺部给药
J Control Release. 2006 Jun 12;113(1):9-14. doi: 10.1016/j.jconrel.2006.03.014. Epub 2006 Mar 28.
4
Pharmaceutical liposomal drug delivery: a review of new delivery systems and a look at the regulatory landscape.药物脂质体药物递送：新递送系统的综述及监管现状分析。
Drug Deliv. 2016 Nov;23(9):3319-3329. doi: 10.1080/10717544.2016.1177136. Epub 2016 May 5.
5
Pharmacokinetic considerations for targeted drug delivery.药物动力学在靶向药物递送中的考虑因素。
Adv Drug Deliv Rev. 2013 Jan;65(1):139-47. doi: 10.1016/j.addr.2012.11.006. Epub 2012 Dec 29.
6
[Methods to increase the encapsulation efficiency for liposomal drugs].[提高脂质体药物包封率的方法]
Acta Pharm Hung. 2008;78(2):69-74.
7
Liposomal drug delivery systems: from concept to clinical applications.脂质体药物递送系统：从概念到临床应用。
Adv Drug Deliv Rev. 2013 Jan;65(1):36-48. doi: 10.1016/j.addr.2012.09.037. Epub 2012 Oct 1.
8
Anti-CD19-targeted liposomal doxorubicin improves the therapeutic efficacy in murine B-cell lymphoma and ameliorates the toxicity of liposomes with varying drug release rates.抗CD19靶向脂质体阿霉素提高了小鼠B细胞淋巴瘤的治疗效果，并改善了不同药物释放速率的脂质体的毒性。
Clin Cancer Res. 2005 May 1;11(9):3567-73. doi: 10.1158/1078-0432.CCR-04-2517.
9
Recent trends in drug delivery systems: liposomal drug delivery system--preparation and characterisation.药物递送系统的最新趋势：脂质体药物递送系统——制备与表征
Indian J Exp Biol. 1997 Aug;35(8):801-9.
10
Liposomal drug formulations in the treatment of rheumatoid arthritis.脂质体药物制剂在类风湿关节炎治疗中的应用。
Mol Pharm. 2011 Aug 1;8(4):1002-15. doi: 10.1021/mp2000742. Epub 2011 Jun 17.

引用本文的文献

1
Improving dexamethasone drug loading and efficacy in treating rheumatoid arthritis via liposome: Focusing on inflammation and molecular mechanisms.通过脂质体提高地塞米松治疗类风湿性关节炎的载药量和疗效：聚焦炎症与分子机制
Animal Model Exp Med. 2025 Jan;8(1):5-19. doi: 10.1002/ame2.12518. Epub 2024 Dec 3.
2
Advancements in cyclodextrin-based controlled drug delivery: Insights into pharmacokinetic and pharmacodynamic profiles.基于环糊精的控释药物递送的进展：对药代动力学和药效学特征的见解。
Heliyon. 2024 Oct 30;10(21):e39917. doi: 10.1016/j.heliyon.2024.e39917. eCollection 2024 Nov 15.
3
A Comprehensive Review of the Strategies to Reduce Retinoid-Induced Skin Irritation in Topical Formulation.

本文引用的文献

1
Distribution and metabolism of lipsome-encapsulated and free 1-beta-D-arabinofuranosylcytosine (Ara-C) in dog and mouse tissues.
J Pharmacol Exp Ther. 1982 Aug;222(2):324-30.
2
Reversible depression of the reticuloendothelial system by liposomes.脂质体对网状内皮系统的可逆性抑制作用
Biochim Biophys Acta. 1982 Feb 25;714(3):479-85. doi: 10.1016/0304-4165(82)90157-x.
3
Comparative properties and methods of preparation of lipid vesicles (liposomes).脂质囊泡（脂质体）的比较性质及制备方法
局部制剂中减少类维生素A引起的皮肤刺激的策略综述
Dermatol Res Pract. 2024 Aug 17;2024:5551774. doi: 10.1155/2024/5551774. eCollection 2024.
4
Technological Advances in a Therapy of Primary Open-Angle Glaucoma: Insights into Current Nanotechnologies.原发性开角型青光眼治疗中的技术进展：对当前纳米技术的见解
J Clin Med. 2023 Sep 6;12(18):5798. doi: 10.3390/jcm12185798.
5
Lipid-based nanosystems for targeting bone implant-associated infections: current approaches and future endeavors.用于靶向骨植入物相关感染的基于脂质的纳米系统：当前方法和未来努力。
Drug Deliv Transl Res. 2021 Feb;11(1):72-85. doi: 10.1007/s13346-020-00791-8.
6
Study on intracellular delivery of liposome encapsulated quantum dots using advanced fluorescence microscopy.使用先进荧光显微镜研究脂质体包裹量子点的细胞内传递。
Sci Rep. 2019 Jul 19;9(1):10504. doi: 10.1038/s41598-019-46732-5.
7
Sterically Stabilized RIPL Peptide-Conjugated Nanostructured Lipid Carriers: Characterization, Cellular Uptake, Cytotoxicity, and Biodistribution.空间稳定的RIPL肽缀合纳米结构脂质载体：表征、细胞摄取、细胞毒性和生物分布
Pharmaceutics. 2018 Oct 23;10(4):199. doi: 10.3390/pharmaceutics10040199.
8
A Light-Triggered Mesenchymal Stem Cell Delivery System for Photoacoustic Imaging and Chemo-Photothermal Therapy of Triple Negative Breast Cancer.用于三阴性乳腺癌光声成像和化学光热疗法的光触发间充质干细胞递送系统
Adv Sci (Weinh). 2018 Aug 24;5(10):1800382. doi: 10.1002/advs.201800382. eCollection 2018 Oct.
9
Essential Dynamics of an Effective Phototherapeutic Drug in a Nanoscopic Delivery Vehicle: Psoralen in Ethosomes for Biofilm Treatment.纳米递送载体中有效光疗药物的基本动力学：用于生物膜治疗的乙磺酰体中的补骨脂素
ACS Omega. 2017 May 31;2(5):1850-1857. doi: 10.1021/acsomega.7b00187. Epub 2017 May 5.
10
Direct and enhanced delivery of nanoliposomes of anti schizophrenic agent to the brain through nasal route.抗精神分裂症药物纳米脂质体通过鼻腔途径直接且增强地递送至大脑。
Saudi Pharm J. 2017 Mar;25(3):346-358. doi: 10.1016/j.jsps.2016.07.003. Epub 2016 Aug 5.
Annu Rev Biophys Bioeng. 1980;9:467-508. doi: 10.1146/annurev.bb.09.060180.002343.
4
Doxorubicin and 5-fluorouracil plasma concentrations and detectability in parotid saliva.多柔比星和5-氟尿嘧啶在腮腺唾液中的血浆浓度及可检测性。
Eur J Clin Pharmacol. 1983;24(2):261-6. doi: 10.1007/BF00613829.
5
Liposome disposition in vivo. VI: Delivery to the lung.
J Pharm Sci. 1984 Feb;73(2):203-6. doi: 10.1002/jps.2600730214.
6
Intrahepatic uptake and processing of intravenously injected small unilamellar phospholipid vesicles in rats.大鼠体内静脉注射的小单层磷脂囊泡的肝内摄取与处理
Biochim Biophys Acta. 1984 Mar 14;770(2):195-202. doi: 10.1016/0005-2736(84)90130-5.
7
Physiology and physiopathology of the reticuloendothelial system.网状内皮系统的生理学与病理生理学
Arch Intern Med. 1970 Dec;126(6):1031-52.
8
Technetium-labelled liposome imaging for deep-seated infection.锝标记脂质体成像用于深部感染
Br J Radiol. 1985 Jan;58(685):35-9. doi: 10.1259/0007-1285-58-685-35.
9
Phagocytic function in the isolated perfused rat liver. An experimental model.大鼠离体灌注肝脏中的吞噬功能。一种实验模型。
J Hepatol. 1985;1(2):153-66. doi: 10.1016/s0168-8278(85)80763-7.
10
Effect of the intra-articular injection of lutetium-177 in chelator liposomes on the progress of an experimental arthritis in rabbits.关节内注射螯合脂质体包裹的镥-177对兔实验性关节炎进展的影响。
Clin Exp Rheumatol. 1985 Jul-Sep;3(3):237-42.