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重症监护病房中的急性肾损伤:发病率及预后的当前趋势

Acute kidney injury in the intensive care unit: current trends in incidence and outcome.

作者信息

Cruz Dinna N, Ronco Claudio

出版信息

Crit Care. 2007;11(4):149. doi: 10.1186/cc5965.

DOI:10.1186/cc5965
PMID:17666115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2206527/
Abstract

Acute kidney injury (AKI) is a common clinical problem with significant clinical and economic consequences. A number of studies point to a rising incidence of AKI in the hospital and in the intensive care unit over the past several years, and an increase in the degree of co-morbidity associated with it. Recent evidence suggests that there has been some improvement in outcomes over time. Nevertheless, the mortality associated with AKI remains unacceptably high, and further work is needed. Recently developed consensus definitions will be useful in this regard.

摘要

急性肾损伤(AKI)是一个常见的临床问题,会产生重大的临床和经济后果。多项研究表明,在过去几年中,医院和重症监护病房中AKI的发病率呈上升趋势,且与之相关的合并症程度也有所增加。最近的证据表明,随着时间的推移,治疗结果已有一定改善。然而,与AKI相关的死亡率仍然高得令人无法接受,仍需进一步开展工作。最近制定的共识定义在这方面将有所帮助。

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本文引用的文献

1
Changes in the incidence and outcome for early acute kidney injury in a cohort of Australian intensive care units.澳大利亚重症监护病房队列中早期急性肾损伤的发病率和转归变化
Crit Care. 2007;11(3):R68. doi: 10.1186/cc5949.
2
Emerging biomarkers of acute kidney injury.急性肾损伤的新兴生物标志物
Contrib Nephrol. 2007;156:203-12. doi: 10.1159/000102085.
3
Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury.急性肾损伤网络:改善急性肾损伤预后的倡议报告
Crit Care. 2007;11(2):R31. doi: 10.1186/cc5713.
4
The rise of prevalence and the fall of mortality of patients with acute renal failure: what the analysis of two databases does and does not tell us.急性肾衰竭患者患病率的上升与死亡率的下降:两个数据库的分析告诉了我们什么以及未告诉我们什么。
J Am Soc Nephrol. 2006 Apr;17(4):923-5. doi: 10.1681/ASN.2006020152. Epub 2006 Mar 15.
5
Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001.1992年至2001年医疗保险受益人中急性肾衰竭的发病率和死亡率。
J Am Soc Nephrol. 2006 Apr;17(4):1135-42. doi: 10.1681/ASN.2005060668. Epub 2006 Feb 22.
6
Declining mortality in patients with acute renal failure, 1988 to 2002.1988年至2002年急性肾衰竭患者死亡率的下降情况
J Am Soc Nephrol. 2006 Apr;17(4):1143-50. doi: 10.1681/ASN.2005091017. Epub 2006 Feb 22.
7
Has mortality from acute renal failure decreased? A systematic review of the literature.急性肾衰竭导致的死亡率下降了吗?一项文献系统综述。
Am J Med. 2005 Aug;118(8):827-32. doi: 10.1016/j.amjmed.2005.01.069.
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Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group.急性肾衰竭——定义、预后指标、动物模型、液体治疗及信息技术需求:急性透析质量倡议(ADQI)小组第二次国际共识会议
Crit Care. 2004 Aug;8(4):R204-12. doi: 10.1186/cc2872. Epub 2004 May 24.