Aydin Sayime, Ertugrul Bulent, Gultekin Berna, Uyar Guliz, Kir Erkin
The Hospital of Dumlupinar University, Department of Ophthalmology, Kutahya, Turkey.
BMC Infect Dis. 2007 Jul 31;7:87. doi: 10.1186/1471-2334-7-87.
Endophthalmitis is the inflammatory response to invasion of the eye with bacteria or fungi. The incidence of endophthalmitis after cataract surgery varies between 0.072-0.13 percent. Treatment of endophthalmitis with fungal etiology is difficult.
Case 1: A 71-year old male diabetic patient developed postoperative endophthalmitis due to Aspergillus flavus. The patient was treated with topical amphotericin B ophthalmic solution, intravenous (IV) liposomal amphotericin-B and caspofungin following vitrectomy. Case 2: A 72-year old male cachectic patient developed postoperative endophthalmitis due to Scopulariopsis spp. The patient was treated with topical and IV voriconazole and caspofungin.
Aspergillus spp. are responsible of postoperative fungal endophthalmitis. Endophthalmitis caused by Scopulariopsis spp. is a very rare condition. The two cases were successfully treated with local and systemic antifungal therapy.
眼内炎是眼部受到细菌或真菌侵袭后的炎症反应。白内障手术后眼内炎的发生率在0.072%至0.13%之间。真菌性眼内炎的治疗较为困难。
病例1：一名71岁男性糖尿病患者因黄曲霉引发术后眼内炎。患者在玻璃体切除术后接受了局部两性霉素B眼药水、静脉注射脂质体两性霉素B和卡泊芬净治疗。病例2：一名72岁男性恶病质患者因拟青霉属引发术后眼内炎。患者接受了局部和静脉注射伏立康唑以及卡泊芬净治疗。
曲霉菌属是术后真菌性眼内炎的病因。拟青霉属引起的眼内炎是一种非常罕见的病症。这两个病例通过局部和全身抗真菌治疗均获成功。
