用于微波消融的内部冷却天线：在离体和活体猪肝脏中的研究结果
Internally cooled antenna for microwave ablation: results in ex vivo and in vivo porcine livers.
作者信息
Wang Yang, Sun Yuanyuan, Feng Lei, Gao Yongyan, Ni Xiaoxia, Liang Ping
机构信息
Department of Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853 China.
Department of Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853 China.
出版信息
Eur J Radiol. 2008 Aug;67(2):357-361. doi: 10.1016/j.ejrad.2007.07.015. Epub 2007 Sep 4.
PURPOSE
To evaluate the performance of microwave ablation with an internally cooled antenna in ex vivo and in vivo porcine livers.
MATERIALS AND METHODS
Microwave ablations were performed in ex vivo and in vivo porcine livers with a 1.9 mm-diameter 2450 MHz microwave needle antenna. Four power settings (50, 60, 70 and 80 W) were used in this study, while application time was fixed at 10 min. Diameters of the coagulation zone were observed on gross specimens.
RESULTS
Excessive elongation of coagulation along the needle shaft was not encountered in all ablations. An arrow-shaped charring was observed. As the power increases, the long-axis coagulation diameter for in vivo liver increased significantly (P<.05). The short-axis coagulation diameter for in vivo liver was significantly smaller than that for ex vivo liver (P<.05) but not statistically different among the four power settings. After 10 min of ablation at 80 W, the short-axis and long-axis coagulation diameter for in vivo liver was 4.92+/-0.15 cm and 2.37+/-0.10 cm, respectively.
CONCLUSION
The internally cooled microwave antenna may be advantageous to minimize collateral damages.
目的
评估采用内部冷却天线的微波消融在离体和活体猪肝脏中的性能。
材料与方法
使用直径1.9毫米、2450兆赫的微波针状天线对离体和活体猪肝脏进行微波消融。本研究采用四种功率设置（50、60、70和80瓦），同时施加时间固定为10分钟。在大体标本上观察凝固区的直径。
结果
在所有消融中均未出现沿针轴的凝固过度延长情况。观察到呈箭头状的炭化。随着功率增加，活体肝脏的长轴凝固直径显著增加（P<0.05）。活体肝脏的短轴凝固直径显著小于离体肝脏（P<0.05），但在四种功率设置之间无统计学差异。在80瓦功率下消融10分钟后，活体肝脏的短轴和长轴凝固直径分别为4.92±0.15厘米和2.37±0.10厘米。
结论
内部冷却的微波天线可能有利于将附带损伤降至最低。
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