Viner R M, Taylor B
Department of Paediatrics, University College Hospital, London, UK.
J Epidemiol Community Health. 2007 Oct;61(10):902-7. doi: 10.1136/jech.2005.038117.
The aim of the study was to determine outcomes in adult life of binge drinking in adolescence in a national birth cohort.
Longitudinal birth cohort: 1970 British Birth Cohort Study surveys at 16 years (1986) and 30 years (2000).
A total of 11 622 subjects participated at age 16 years and 11 261 subjects participated at age 30 years.
At the age of 16 years, data on binge drinking (defined as two or more episodes of drinking four or more drinks in a row in the previous 2 weeks) and frequency of habitual drinking in the previous year were collected. Thirty-year outcomes recorded were alcohol dependence/abuse (CAGE questionnaire), regular weekly alcohol consumption (number of units), illicit drug use, psychological morbidity (Malaise Inventory) and educational, vocational and social history.
17.7% of participants reported binge drinking in the previous 2 weeks at the age of 16 years. Adolescent binge drinking predicted an increased risk of adult alcohol dependence (OR 1.6, 95% CI 1.3 to 2.0), excessive regular consumption (OR 1.7, 95% CI 1.4 to 2.1), illicit drug use (OR 1.4, 95% CI 1.1 to 1.8), psychiatric morbidity (OR 1.4, 95% CI 1.1 to 1.9), homelessness (OR 1.6, 95% CI 1.1 to 2.4), convictions (1.9, 95% CI 1.4 to 2.5), school exclusion (OR 3.9, 95% CI 1.9 to 8.2), lack of qualifications (OR 1.3, 95% CI 1.1 to 1.6), accidents (OR 1.4, 95% CI 1.1 to 1.6) and lower adult social class, after adjustment for adolescent socioeconomic status and adolescent baseline status of the outcome under study. These findings were largely unchanged in models including both adolescent binge drinking and habitual frequent drinking as main effects.
Adolescent binge drinking is a risk behaviour associated with significant later adversity and social exclusion. These associations appear to be distinct from those associated with habitual frequent alcohol use. Binge drinking may contribute to the development of health and social inequalities during the transition from adolescence to adulthood.
本研究旨在确定全国出生队列中青少年期暴饮在成年后的影响。
纵向出生队列研究：1970年英国出生队列研究在16岁（1986年）和30岁（2000年）时进行调查。
共有11622名受试者在16岁时参与，11261名受试者在30岁时参与。
在16岁时，收集有关暴饮（定义为在前两周内连续两次或更多次每次饮用四杯或更多酒）及上一年习惯性饮酒频率的数据。记录的30岁时的结果包括酒精依赖/滥用（CAGE问卷）、每周定期饮酒量（单位数）、非法药物使用、心理疾病（不适量表）以及教育、职业和社会经历。
17.7%的参与者报告在16岁时的前两周有暴饮行为。青少年期暴饮预示着成年后酒精依赖风险增加（比值比1.6，95%置信区间1.3至2.0）、定期过量饮酒（比值比1.7，95%置信区间1.4至2.1）、非法药物使用（比值比1.4，95%置信区间1.1至1.8）、精神疾病（比值比1.4，95%置信区间1.1至1.9）、无家可归（比值比1.6，95%置信区间1.1至2.4）、被定罪（比值比1.9，95%置信区间1.4至2.5）、被学校开除（比值比3.9，95%置信区间1.9至8.2）、缺乏学历（比值比1.3，95%置信区间1.1至1.6）、发生事故（比值比1.4，95%置信区间1.1至1.6）以及成年后社会阶层较低，在对青少年社会经济地位和所研究结果的青少年基线状态进行调整后。在将青少年暴饮和习惯性频繁饮酒均作为主要影响因素的模型中，这些结果基本不变。
青少年期暴饮是一种风险行为，与日后显著的逆境和社会排斥相关。这些关联似乎有别于与习惯性频繁饮酒相关的关联。暴饮可能在从青少年向成年过渡期间导致健康和社会不平等的加剧。
