Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
J Appl Oral Sci. 2015 Jan-Feb;23(1):14-8. doi: 10.1590/1678-775720140124.
This study assessed the effect of fluoride varnishes on the progression of tooth erosion in vitro.
Forty-eight enamel and 60 root dentin samples were previously demineralized (0.1% citric acid, pH 2.5, 30 min), leading to a baseline and erosive wear of 12.9 and 11.4 µm, respectively. The samples were randomly treated (6 h) with a 4% TiF4 varnish (2.45%F-, pH 1.0), a 5.42% NaF varnish (2.45%F-, pH 5.0), a placebo varnish and no varnish (control). The samples were then subjected to erosive pH cycles (4x90 s/day in 0.1% citric acid, intercalated with artificial saliva) for 5 days. The increment of the erosive tooth wear was calculated. In the case of dentin, this final measurement was done with and without the demineralized organic matrix (DOM). Enamel and dentin data were analyzed using ANOVA/Tukey's and Kruskal-Wallis/Dunn tests, respectively (p<0.05).
The TiF4 (mean±s.d: 1.5±1.1 µm) and NaF (2.1±1.7 µm) varnishes significantly reduced enamel wear progression compared to the placebo varnish (3.9±1.1 µm) and control (4.5±0.9 µm). The same differences were found for dentin in the presence and absence of the DOM, respectively: TiF4 (average: 0.97/1.87 µm), NaF (1.03/2.13 µm), placebo varnish (3.53/4.47 µm) and control (3.53/4.36 µm).
The TiF4 and NaF varnishes were equally effective in reducing the progression of tooth erosion in vitro.
本研究评估了氟化物漆对体外牙酸蚀进展的影响。
48 个牙釉质和 60 个牙根牙本质样本之前经过脱矿处理（0.1%柠檬酸，pH 值 2.5，30 分钟），导致基线和侵蚀性磨损分别为 12.9 和 11.4 µm。样本被随机处理（6 小时）使用 4%TiF4 漆（2.45%F-，pH 值 1.0）、5.42%NaF 漆（2.45%F-，pH 值 5.0）、安慰剂漆和无漆（对照）。然后，样本被暴露在侵蚀性 pH 循环中（每天 4 次，每次 90 秒，在 0.1%柠檬酸中，中间穿插人工唾液），持续 5 天。计算了侵蚀性牙磨损的增量。对于牙本质，在有和没有脱矿有机基质（DOM）的情况下进行了最终测量。牙釉质和牙本质数据分别使用方差分析/Tukey 检验和 Kruskal-Wallis/Dunn 检验进行分析（p<0.05）。
TiF4（平均值±标准差：1.5±1.1 µm）和 NaF（2.1±1.7 µm）漆与安慰剂漆（3.9±1.1 µm）和对照（4.5±0.9 µm）相比，显著减少了牙釉质磨损的进展。对于有和没有 DOM 的牙本质，也发现了相同的差异：TiF4（平均值：0.97/1.87 µm）、NaF（1.03/2.13 µm）、安慰剂漆（3.53/4.47 µm）和对照（3.53/4.36 µm）。
TiF4 和 NaF 漆在体外均能有效减少牙酸蚀的进展。
