Kuna Lucija, Jakab Jelena, Smolic Robert, Raguz-Lucic Nikola, Vcev Aleksandar, Smolic Martina
Department of Pharmacology and Biochemistry, Faculty of Dental Medicine and Health Osijek, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia.
Department of Pathophysiology and Physiology with Immunology, Faculty of Dental Medicine and Health Osijek, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia.
J Clin Med. 2019 Feb 3;8(2):179. doi: 10.3390/jcm8020179.
Peptic ulcer is a chronic disease affecting up to 10% of the world's population. The formation of peptic ulcers depends on the presence of gastric juice pH and the decrease in mucosal defenses. Non-steroidal anti-inflammatory drugs (NSAIDs) and infection are the two major factors disrupting the mucosal resistance to injury. Conventional treatments of peptic ulcers, such as proton pump inhibitors (PPIs) and histamine-2 (H2) receptor antagonists, have demonstrated adverse effects, relapses, and various drug interactions. On the other hand, medicinal plants and their chemical compounds are useful in the prevention and treatment of numerous diseases. Hence, this review presents common medicinal plants that may be used for the treatment or prevention of peptic ulcers.
消化性溃疡是一种慢性病，全球高达10%的人口受其影响。消化性溃疡的形成取决于胃液pH值以及黏膜防御功能的降低。非甾体抗炎药（NSAIDs）和感染是破坏黏膜抗损伤能力的两大主要因素。消化性溃疡的传统治疗方法，如质子泵抑制剂（PPI）和组胺-2（H2）受体拮抗剂，已显示出不良反应、复发以及各种药物相互作用。另一方面，药用植物及其化合物在多种疾病的预防和治疗中很有用。因此，本综述介绍了可能用于治疗或预防消化性溃疡的常见药用植物。
