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不同牙膏对预防牙釉质侵蚀的影响。

Impact of different toothpastes on the prevention of erosion.

作者信息

Lussi A, Megert B, Eggenberger D, Jaeggi T

机构信息

Department of Preventive, Restorative and Pediatric Dentistry, University of Bern, Bern, Switzerland.

出版信息

Caries Res. 2008;42(1):62-7. doi: 10.1159/000112517. Epub 2007 Dec 17.

Abstract

The aim of the present study was to test the impact of different toothpastes on the prevention of erosion. Enamel demineralization and remineralization were monitored using surface microhardness (SMH) measurements. Human enamel specimens were treated following two different procedures: (1) incubation in toothpaste slurry followed by acid softening and artificial saliva exposure; (2) acid softening followed by incubation in toothpaste slurry and artificial saliva exposure. For the control procedure, toothpaste treatment was excluded. The following toothpastes were tested: Zendium, Sensodyne Proschmelz (Pronamel), Prodent Rocket Power, Meridol and Signal active. Normalized SMH values compared to the baseline (= 1.00) after 1-hour artificial saliva exposure for procedure 1 (respectively for procedure 2) were as follows (mean: 95% CI): Sensodyne Proschmelz 0.97: 0.93, 1.00 (0.92: 0.90, 0.94), Zendium 0.97: 0.94, 1.00 (0.89: 0.83, 0.95), Meridol 0.97: 0.94, 1.00 (0.94: 0.92, 0.96), Signal active 0.94: 0.91, 0.97 (0.95: 0.91, 0.99), Prodent Rocket Power 0.92: 0.90, 0.94 (0.93: 0.89, 0.97) and control 0.91: 0.88, 0.94. Further exposure to artificial saliva for up to 4 h showed no significant improvement of SMH. Regression analyses revealed a significant impact of the applied procedure. Incubation in toothpaste slurries before the acid challenge seems to be favorable to prevent erosion. None of the tested toothpastes showed statistically significant better protection than another against an erosive attack.

摘要

本研究的目的是测试不同牙膏对预防牙釉质侵蚀的影响。使用表面显微硬度(SMH)测量来监测牙釉质的脱矿质和再矿化。人类牙釉质标本按照两种不同程序进行处理:(1)在牙膏浆液中孵育,随后进行酸软化和人工唾液暴露;(2)酸软化,随后在牙膏浆液中孵育和人工唾液暴露。对于对照程序,排除牙膏处理。测试了以下几种牙膏:舒适达专业修复(Pronamel)、皓乐齿Proschmelz(珍亮)、高露洁劲爽、美尔根和Signal active。对于程序1(分别对于程序2),在1小时人工唾液暴露后与基线(=1.00)相比的标准化SMH值如下(均值:95%置信区间):舒适达专业修复0.97:0.93,1.00(0.92:0.90,0.94),皓乐齿Proschmelz 0.97:0.94,1.00(0.89:0.83,0.95),美尔根0.97:0.94,1.00(0.94:0.92,0.96),Signal active 0.94:0.91,0.97(0.95:0.91,0.99),高露洁劲爽0.92:0.90,0.94(0.93:0.89,0.97),对照0.91:0.88,0.94。进一步暴露于人工唾液长达4小时未显示SMH有显著改善。回归分析显示所应用程序有显著影响。在酸刺激之前在牙膏浆液中孵育似乎有利于预防侵蚀。所测试的牙膏中没有一种在防止侵蚀攻击方面显示出比另一种在统计学上有显著更好的保护作用。

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