Carattoli A
Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.
Clin Microbiol Infect. 2008 Jan;14 Suppl 1:117-23. doi: 10.1111/j.1469-0691.2007.01851.x.
Food-producing animals are the primary reservoir of zoonotic pathogens, and the detection of extended spectrum beta-lactamase (ESBL) producers among Escherichia coli and Salmonella strains has increased in recent years. ESBLs are widely detected in various human medical institutions but they are not so frequently reported in the bacterial population circulating in animals. This could indicate that these enzymes are less prevalent in animals than in humans, but also that they have not been extensively sought. The increasing occurrence of ESBL producers in animals is highlighted and discussed in this review with respect to the circulation of these resistance traits also among human pathogens.
食用动物是动物源性病原体的主要宿主,近年来在大肠杆菌和沙门氏菌菌株中检测到的超广谱β-内酰胺酶(ESBL)产生菌有所增加。ESBL在各类人类医疗机构中广泛检测到,但在动物中传播的细菌群体中报告较少。这可能表明这些酶在动物中不如在人类中普遍,但也可能是因为尚未对其进行广泛搜索。本综述着重探讨了动物中ESBL产生菌的日益增多,并讨论了这些耐药性状在人类病原体中的传播情况。