Kojima Kazuo, Ohno Takamasa, Inoue Makoto, Mizukami Hajime, Nagatsu Akito
Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho-ku, Nagoya, Japan.
Chem Pharm Bull (Tokyo). 2008 Feb;56(2):173-5. doi: 10.1248/cpb.56.173.
A new furopyranone, phellifuropyranone A, was isolated from fruit bodies of wild Phellinus linteus as well as phelligridin G, and their chemical structures were determined by various spectroscopic methods including measurement of NMR spectra. Phellifuropyranone A together with meshimakobnol A and meshimakobnol B showed antiproliferative activity against mouse melanoma cells and human lung cancer cells in vitro.
从野生桑黄的子实体中分离出一种新的呋喃吡喃酮——桑黄呋喃吡喃酮A以及桑黄环肽G,通过包括核磁共振光谱测量在内的各种光谱方法确定了它们的化学结构。桑黄呋喃吡喃酮A与间苯三酚A和间苯三酚B在体外对小鼠黑色素瘤细胞和人肺癌细胞具有抗增殖活性。