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本文引用的文献

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Development and evaluation of a gamma-interferon assay for tuberculosis in badgers (Meles meles).獾（欧洲獾）结核病γ干扰素检测方法的开发与评估。
Tuberculosis (Edinb). 2008 May;88(3):235-43. doi: 10.1016/j.tube.2007.11.001. Epub 2007 Dec 20.
2
Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial.广泛捕杀獾对牛结核病的影响：来自大规模田间试验的总结分析
Int J Infect Dis. 2007 Jul;11(4):300-8. doi: 10.1016/j.ijid.2007.04.001. Epub 2007 Jun 12.
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Development and evaluation of a test for tuberculosis in live European badgers (Meles meles) based on measurement of gamma interferon mRNA by real-time PCR.基于实时PCR法检测γ干扰素mRNA对欧洲活体獾结核病进行检测的方法开发与评估
J Clin Microbiol. 2007 Aug;45(8):2398-403. doi: 10.1128/JCM.00292-07. Epub 2007 May 30.
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The role of wild animal populations in the epidemiology of tuberculosis in domestic animals: how to assess the risk.野生动物种群在家畜结核病流行病学中的作用：如何评估风险。
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The impact of badger removal on the control of tuberculosis in cattle herds in Ireland.獾捕杀对爱尔兰牛群结核病控制的影响。
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Improved serodetection of Mycobacterium bovis infection in badgers (Meles meles) using multiantigen test formats.使用多抗原检测形式改进对獾（欧洲獾）牛分枝杆菌感染的血清学检测
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Pathology of natural Mycobacterium bovis infection in European badgers (Meles meles) and its relationship with bacterial excretion.欧洲獾自然感染牛分枝杆菌的病理学及其与细菌排泄的关系。
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Role of infected, non-diseased badgers in the pathogenesis of tuberculosis in the badger.受感染但未患病的獾在獾结核病发病机制中的作用。
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用于检测欧亚獾（Meles meles）结核病的BrockTB stat-pak检测法的验证以及疾病严重程度对诊断准确性的影响。

Validation of the BrockTB stat-pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy.

作者信息

Chambers Mark A, Crawshaw Tim, Waterhouse Sue, Delahay Richard, Hewinson R Glyn, Lyashchenko Konstantin P

机构信息

TB Research Group, Department of Statutory and Exotic Bacterial Diseases, Veterinary Laboratories Agency Weybridge, New Haw, Surrey KT15 3NB, United Kingdom.

出版信息

J Clin Microbiol. 2008 Apr;46(4):1498-500. doi: 10.1128/JCM.02117-07. Epub 2008 Feb 13.

DOI:10.1128/JCM.02117-07
PMID:18272706
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2292970/
Abstract

A lateral-flow immunoassay (BrockTB Stat-Pak) for detecting tuberculosis in Eurasian badgers was 49% sensitive and 93% specific against culture for M. bovis (n = 1,464) at necropsy. However, the sensitivity was significantly higher (66 to 78%) in animals with more severe tuberculosis, indicating that the BrockTB Stat-Pak may be useful for the detection of badgers with the greatest risk of transmitting disease.

摘要

一种用于检测欧亚獾结核病的侧向流动免疫分析（BrockTB Stat-Pak），在尸检时针对牛分枝杆菌培养物的敏感性为49%，特异性为93%（n = 1464）。然而，在患有更严重结核病的动物中，敏感性显著更高（66%至78%），这表明BrockTB Stat-Pak可能有助于检测具有最大疾病传播风险的獾。