Toro Roberto, Fox Peter T, Paus Tomás
Brain & Body Centre, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
Cereb Cortex. 2008 Nov;18(11):2553-9. doi: 10.1093/cercor/bhn014. Epub 2008 Feb 21.
Understanding the interactions among different brain regions is fundamental to our understanding of brain function. Here we describe a complete map of functional connections in the human brain derived by an automatic meta-analysis of 825 neuroimaging articles, representing 3402 experiments. The likelihood of a functional connection between regions was estimated by studying the interdependence of their "activity," as reported in each experiment, across all experiments. We obtained a dense coactivation map that recovers some fundamental principles of the brain's functional connectivity, such as the symmetric interhemispheric connections, and important functional networks, such as the fronto-parietal attention network, the resting state network and the motor network.
理解不同脑区之间的相互作用是我们理解脑功能的基础。在此，我们描述了通过对825篇神经影像学文章（代表3402项实验）进行自动荟萃分析得出的人类大脑功能连接完整图谱。通过研究每个实验中所报告的各脑区“活动”在所有实验中的相互依赖性，估算了脑区之间功能连接的可能性。我们获得了一张密集的共激活图谱，该图谱重现了大脑功能连接的一些基本原理，如对称的半球间连接，以及一些重要的功能网络，如额顶叶注意力网络、静息态网络和运动网络。
