Bourne R R A, Foster P J, Bunce C, Peto T, Hitchings R A, Khaw P T, Seah S K L, Garway-Heath D F
Huntingdon Glaucoma Diagnostic & Research Centre, Department Ophthalmology, Hinchingbrooke Hospital, Huntingdon PE29 6NT, UK.
Br J Ophthalmol. 2008 Mar;92(3):303-9. doi: 10.1136/bjo.2007.123273.
BACKGROUND/AIMS: To investigate the correlation between optic disc parameters and their association with demographic variables in a Chinese population.
Disc data were obtained from 929 subjects aged > or = 40 years from the Tanjong Pagar glaucoma survey of Singapore, using a novel planimetric method of sequential stereo-photographs. Biometric data (refractive error, keratometry, axial length, anterior chamber depth, lens thickness) were used to calculate ocular magnification. Camera magnification was quantified with a model eye. A "normal" dataset of 622 subjects was generated by exclusion of subjects with abnormal results on psychophysical testing, an occludable angle or an intraocular pressure > 97.5th percentile in either eye.
Median disc area (DA), cup area (CA), and rim area (RA) were 2.09 (range 1.28-4.01) mm2, 0.69 (0.01-1.90) mm2 and 1.38 (0.82-2.50) mm2, respectively. There was strong evidence of an association between DA and RA (Spearman's rho 0.624, p<0.001). DA and RA were significantly greater in men (median DA = 2.20; range 1.30-3.56; median RA, 1.45; range 0.85-2.30) than women (median DA, 2.00; range 1.28-4.01; median RA, 1.36; range 0.82-2.49, p<0.001). DA increased with age (Spearman's rho 0.115, p = 0.004), while RA was unrelated (rho -0.041; p = 0.308).
The morphometric characteristics of optic discs in Chinese Singaporeans are very similar to those described in other groups, with the temporal sector rim having the smallest area. Disc and rim areas vary with sex (men > women). Disc area (but not that of the rim) increases with age.
背景/目的：研究中国人群中视盘参数之间的相关性及其与人口统计学变量的关系。
采用一种新颖的顺序立体摄影平面测量法，从新加坡丹戎巴葛青光眼调查中929名年龄≥40岁的受试者获取视盘数据。生物测量数据（屈光不正、角膜曲率、眼轴长度、前房深度、晶状体厚度）用于计算眼放大率。用模型眼对视相机放大率进行量化。通过排除在心理物理学测试结果异常、有闭角或任何一只眼眼压>第97.5百分位数的受试者，生成了一个包含622名受试者的“正常”数据集。
视盘面积（DA）、杯盘面积（CA）和视盘边缘面积（RA）的中位数分别为2.09（范围1.28 - 4.01）mm²、0.69（0.01 - 1.90）mm²和1.38（0.82 - 2.50）mm²。有充分证据表明DA与RA之间存在关联（斯皮尔曼等级相关系数ρ为0.624，p<0.001）。男性的DA和RA显著大于女性（DA中位数 = 2.20；范围1.30 - 3.56；RA中位数，1.45；范围0.85 - 2.30）（女性DA中位数，2.00；范围1.28 - 4.01；RA中位数，1.36；范围0.82 - 2.49，p<0.001）。DA随年龄增加（斯皮尔曼等级相关系数ρ为0.115，p = 0.004），而RA与之无关（ρ为 -0.041；p = 0.308）。
新加坡华人的视盘形态特征与其他群体描述的非常相似，颞侧视盘边缘面积最小。视盘和视盘边缘面积因性别而异（男性>女性）。视盘面积（而非视盘边缘面积）随年龄增加。
