Guerra Humberto, Palomino Juan Carlos, Falconí Eduardo, Bravo Francisco, Donaires Ninoska, Van Marck Eric, Portaels Françoise
Universidad Peruana Cayetano Heredia, Lima, Perú.
Emerg Infect Dis. 2008 Mar;14(3):373-7. doi: 10.3201/eid1403.070904.
Eight adult patients (ages 18-58, 5 women) with Buruli ulcer (BU) confirmed by at least 2 diagnostic methods were seen in a 10-year period. Attempts to culture Mycobacterium ulcerans failed. Five patients came from jungle areas, and 3 from the swampy northern coast of Peru. The patients had 1-5 lesions, most of which were on the lower extremities. One patient had 5 clustered gluteal lesions; another patient had 2 lesions on a finger. Three patients were lost to follow-up. All 5 remaining patients had moderate disease. Diverse treatments (antituberculous drugs, World Health Organization [WHO] recommended antimicrobial drug treatment for BU, and for 3 patients, excision surgery) were successful. Only 1 patient (patient 7) received the specific drug treatment recommended by WHO. BU is endemic in Peru, although apparently infrequent. Education of populations and training of health workers are first needed to evaluate and understand the full extent of BU in Peru.
在10年期间，共诊治了8例经至少2种诊断方法确诊的成人布鲁里溃疡（BU）患者（年龄18 - 58岁，5名女性）。溃疡分枝杆菌培养未成功。5例患者来自丛林地区，3例来自秘鲁北部的沼泽海岸。患者有1 - 5处皮损，大部分位于下肢。1例患者有5处簇集性臀部皮损；另1例患者手指有2处皮损。3例患者失访。其余5例患者病情均为中度。多种治疗方法（抗结核药物、世界卫生组织[WHO]推荐的BU抗菌药物治疗，3例患者接受了切除手术）均取得成功。仅1例患者（患者7）接受了WHO推荐的特异性药物治疗。尽管显然不常见，但BU在秘鲁为地方病。首先需要对民众进行教育并对卫生工作者进行培训，以评估和全面了解秘鲁BU的情况。
