Chu C H, Lo Edward C M
Faculty of Dentistry, The University of Hong Kong, 34 Hospital Road, Hong Kong SAR, China.
J Dent. 2008 Jun;36(6):387-91. doi: 10.1016/j.jdent.2008.02.013. Epub 2008 Apr 18.
This study measured the microhardness of arrested dentinal caries on primary teeth receiving regular fluoride applications after 30 months.
Caries on primary upper anterior teeth of preschool children were randomly assigned to receive 38% silver diamine fluoride every 12 months or 5% sodium fluoride varnish every 3 months. Lesions that were hard on probing were considered arrested. At 30 months, very mobile teeth were extracted, sectioned, and polished and they underwent Knoop hardness number (KHN) measurements at sites below the surface at the center of the carious lesion every 25 microm toward the pulp. Three sets of measurements were made on parallel tracks approximately 150-200 microm apart, and the median KHN at each depth were analyzed.
Five arrested and five soft carious lesions were examined. Within the outer 25-200 microm, the median KHN of arrested carious lesions (range, 20-46 or 196-451 MPa) were greater than those of soft carious lesions (range, 5-20, or 49-196 MPa). The difference between them, however, was not statistically significant. At a distance of 225 microm or more from the surface of the lesion, the median KHN of both groups were between 20 and 30 (196-294 MPa).
The outermost dentinal surface of carious lesions that had been arrested by topical fluoride application was harder than that of active carious lesions. At a distance of 225 microm or more from the lesion surface, the microhardness of both arrested and soft dentinal caries was similar.
本研究测量了在接受定期氟化物应用30个月后乳牙静止性龋损的显微硬度。
将学龄前儿童上颌乳前牙的龋损随机分为两组,一组每12个月接受一次38%的氟化银胺治疗,另一组每3个月接受一次5%的氟化钠 varnish治疗。探诊时质地硬的病变被视为静止性龋。在30个月时,将松动度很大的牙齿拔除、切片并抛光,然后在龋损中心表面以下每隔25微米朝向牙髓的部位进行努氏硬度值(KHN)测量。在相距约150 - 200微米的平行轨迹上进行三组测量,并分析每个深度的中位数KHN。
检查了5个静止性龋损和5个软化性龋损。在最外层25 - 200微米范围内,静止性龋损的中位数KHN(范围为20 - 46或196 - 451兆帕)大于软化性龋损的中位数KHN(范围为5 - 20或49 - 196兆帕)。然而,它们之间的差异无统计学意义。在距病变表面225微米或更远的距离处,两组的中位数KHN均在20至30之间(196 - 294兆帕)。
通过局部应用氟化物而静止的龋损最外层牙本质表面比活动性龋损的更硬。在距病变表面225微米或更远的距离处,静止性和软化性牙本质龋的显微硬度相似。