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积雪草中的两种新黄酮类化合物。

Two new flavonoids from Centella asiatica (Linn.).

作者信息

Subban Ravi, Veerakumar A, Manimaran R, Hashim K M, Balachandran Indira

出版信息

J Nat Med. 2008 Jul;62(3):369-73. doi: 10.1007/s11418-008-0229-0. Epub 2008 Feb 13.

DOI:10.1007/s11418-008-0229-0
PMID:18404308
Abstract

Two new flavonoids named castilliferol 1 and castillicetin 2, as well as a known compound, isochlorogenic acid 3, were isolated from the whole plant of Centella asiatica. Isolates 1 and 2 exhibited good antioxidant activity using 2,2-diphenyl-1-picryl hydrazyl radical solution with IC(50) values of 23.10 and 13.30, respectively. The structures of these isolates were determined by analytical and spectral data, including 1-D and 2-D NMR spectra.

摘要

从积雪草全草中分离出两种新的黄酮类化合物,分别命名为积雪草醇1和积雪草黄素2,以及一种已知化合物异绿原酸3。分离物1和2在使用2,2-二苯基-1-苦基肼自由基溶液时表现出良好的抗氧化活性,IC(50)值分别为23.10和13.30。这些分离物的结构通过分析和光谱数据确定,包括一维和二维核磁共振光谱。

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