Braun B, Clarkson P M, Freedson P S, Kohl R L
Dept. of Nutritional Sciences, University of California, Berkeley 94720.
Int J Sport Nutr. 1991 Dec;1(4):353-65. doi: 10.1123/ijsn.1.4.353.
The effects of dietary supplementation with Coenzyme Q10 (CoQ10), a reputed performance enhancer and antioxidant, on physiological and biochemical parameters were examined. Ten male bicycle racers performed graded cycle ergometry both before and after being given 100 mg per day CoQ10 or placebo for 8 weeks. Analysis of variance showed a significant difference between groups for postsupplementation serum CoQ10. Although both groups demonstrated training related improvements in all physiological parameters over the course of the study, there were no significant differences between the two groups (p > .05). Both groups showed a 21% increase in serum MDA (an index of lipid peroxidation) after the presupplementation exercise test. After 8 weeks this increase was only 5%, and again was identical for both groups. Supplementation with CoQ10 has no measurable effect on cycling performance, VO2max, submaximal physiological parameters, or lipid peroxidation. However, chronic intense training seems to result in marked attenuation of exercise-induced lipid peroxidation.
研究了膳食补充辅酶Q10（CoQ10），一种著名的性能增强剂和抗氧化剂，对生理和生化参数的影响。十名男性自行车赛车手在每天服用100毫克CoQ10或安慰剂8周前后进行了分级自行车测力计测试。方差分析显示补充后血清CoQ10在组间存在显著差异。尽管在研究过程中两组在所有生理参数上都表现出与训练相关的改善，但两组之间没有显著差异（p>.05）。在补充前的运动测试后，两组血清MDA（脂质过氧化指标）均增加21%。8周后，这种增加仅为5%，两组再次相同。补充CoQ10对自行车运动表现、最大摄氧量、次最大生理参数或脂质过氧化没有可测量的影响。然而，长期高强度训练似乎会导致运动诱导的脂质过氧化明显减弱。
