Cavalcanti Adriano, Shirinzadeh Bijan, Kretly Luiz C
CAN Center for Automation in Nanobiotech, Melbourne VIC, Australia.
Nanomedicine. 2008 Jun;4(2):127-38. doi: 10.1016/j.nano.2008.03.001. Epub 2008 May 2.
This work presents an innovative nanorobot architecture based on nanobioelectronics for diabetes. The progressive development toward the therapeutic use of nanorobots should be observed as the natural result from some ongoing and future achievements in biomedical instrumentation, wireless communication, remote power transmission, nanoelectronics, new materials engineering, chemistry, proteomics, and photonics. To illustrate the nanorobot integrated circuit architecture and layout described here, a computational approach with the application of medical nanorobotics for diabetes is simulated using clinical data. Integrated simulation can provide interactive tools for addressing nanorobot choices on sensing, hardware design specification, manufacturing analysis, and methodology for control investigation. In the proposed 3D prototyping, a physician can help the patient to avoid hyperglycemia by means of a handheld device, like a cell phone enclosed with cloth, that is used as a smart portable device to communicate with nanorobots. Therefore, this architecture provides a suitable choice to establish a practical medical nanorobotics platform for in vivo health monitoring.
这项工作展示了一种基于纳米生物电子学的用于糖尿病治疗的创新型纳米机器人架构。纳米机器人治疗用途的逐步发展应被视为生物医学仪器、无线通信、远程电力传输、纳米电子学、新材料工程、化学、蛋白质组学和光子学等当前及未来一些成果的自然产物。为了阐释此处描述的纳米机器人集成电路架构和布局，使用临床数据对应用于糖尿病治疗的医学纳米机器人的计算方法进行了模拟。集成模拟可为解决纳米机器人在传感、硬件设计规格、制造分析以及控制研究方法等方面的选择问题提供交互式工具。在所提出的三维原型中，医生可借助手持设备（如包裹着布的手机）帮助患者避免高血糖，该手持设备用作与纳米机器人通信的智能便携式设备。因此，这种架构为建立用于体内健康监测的实用医学纳米机器人平台提供了合适的选择。
