单剂量阿奇霉素治疗妊娠期衣原体宫颈炎的疗效与耐受性
Efficacy and Tolerance of Single-dose Azithromycin for Treatment of Chlamydial Cervicitis During Pregnancy.
作者信息
Miller J M
机构信息
Department of Obstetrics and Gynecology Louisiana State University Medical Center 1542 Tulane Avenue New Orleans LA 70112-2822 USA.
出版信息
Infect Dis Obstet Gynecol. 1995;3(5):189-92. doi: 10.1155/S1064744995000597.
Abstract
OBJECTIVE
The intent of this study was to determine the efficacy and tolerance of single-dose oral azithromycin in the treatment of pregnant women with endocervical chlamydial carriage.
METHODS
A retrospective review of clinic records over a two-year period identified pregnant patients treated with a single 1-g dose of azithromycin for chlamydial carriage. The side effects and subsequent chlamydial carriage (test of cure) were noted.
RESULTS
A total of 146 pregnant women treated with azithromycin was reviewed. A cure rate of 96% was found. Side effects were reported in 5%.
CONCLUSIONS
A single 1-g oral dose of azithromycin is effective for the treatment of chlamydia and is well tolerated in pregnant women.
摘要
目的
本研究旨在确定单剂量口服阿奇霉素治疗宫颈衣原体携带孕妇的疗效和耐受性。
方法
对两年期间的临床记录进行回顾性分析，确定接受单剂量1克阿奇霉素治疗衣原体携带的孕妇。记录副作用和随后的衣原体携带情况（治愈检测）。
结果
共回顾了146例接受阿奇霉素治疗的孕妇。治愈率为96%。5%的患者报告有副作用。
结论
单剂量1克口服阿奇霉素治疗衣原体有效，且孕妇耐受性良好。
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