• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

来自松果(赤松)的对痤疮有活性的半日花烷型二萜类化合物。

Labdane-type diterpenes active against acne from pine cones (Pinus densiflora).

作者信息

Sultan Md Zakir, Jeon Young-Min, Moon Surk-Sik

机构信息

Department of Chemistry, Kongju National University, Kongju, Korea.

出版信息

Planta Med. 2008 Mar;74(4):449-52. doi: 10.1055/s-2008-1034321.

DOI:10.1055/s-2008-1034321
PMID:18484541
Abstract

Bioassay-guided extraction and fractionation of the aqueous methanolic extract of the cones of Pinus densiflora (Pinaceae) afforded one new labdane-type diterpene aldehyde, 15-nor-14-oxolabda-8(17),12 E-diene-18-oic acid, along with eight known diterpenes. Their structures were elucidated using spectroscopic methods as well as by comparison with previously reported data. The isolates showed antibacterial (Propionibacterium acnes) and antifungal activities.

摘要

对赤松(松科)球果的甲醇水提取物进行生物测定导向的提取和分离,得到一种新的半日花烷型二萜醛,15-降-14-氧代半日花-8(17),12E-二烯-18-酸,以及八种已知的二萜。通过光谱方法并与先前报道的数据进行比较,阐明了它们的结构。分离物显示出抗菌(痤疮丙酸杆菌)和抗真菌活性。

相似文献

1
Labdane-type diterpenes active against acne from pine cones (Pinus densiflora).来自松果(赤松)的对痤疮有活性的半日花烷型二萜类化合物。
Planta Med. 2008 Mar;74(4):449-52. doi: 10.1055/s-2008-1034321.
2
Potential antitumor-promoting diterpenes from the cones of Pinus luchuensis.来自琉球松球果的潜在抗肿瘤促进二萜类化合物。
J Nat Prod. 2002 Dec;65(12):1921-3. doi: 10.1021/np020258y.
3
Diterpenes from "Pini Resina" and their preferential cytotoxic activity under nutrient-deprived condition.来自“Pini Resina”的二萜类化合物及其在营养缺乏条件下的优先细胞毒性活性。
Planta Med. 2006 Oct;72(13):1231-4. doi: 10.1055/s-2006-947189. Epub 2006 Aug 10.
4
Susceptibility of Propionibacterium acnes and Staphylococcus epidermidis to killing by MPO-halide system products. Implication for taurine bromamine as a new candidate for topical therapy in treating acne vulgaris.痤疮丙酸杆菌和表皮葡萄球菌对髓过氧化物酶-卤化物系统产物杀菌作用的敏感性。牛磺酸溴胺作为寻常痤疮局部治疗新候选药物的意义。
Arch Immunol Ther Exp (Warsz). 2006 Jan-Feb;54(1):61-8. doi: 10.1007/s00005-006-0007-1. Epub 2006 Feb 13.
5
Syntheses and antibacterial activities of diterpene catechol derivatives with abietane, totarane and podocarpane skeletons against methicillin-resistant Staphylococcus aureus and Propionibacterium acnes.具有枞烷、罗汉松烷和竹柏烷骨架的二萜儿茶酚衍生物对耐甲氧西林金黄色葡萄球菌和痤疮丙酸杆菌的合成及抗菌活性
Chem Pharm Bull (Tokyo). 2010 Jun;58(6):818-24. doi: 10.1248/cpb.58.818.
6
Diterpenoids from Pinus massoniana resin and their cytotoxicity against A431 and A549 cells.马尾松松脂中二萜类化合物及其对 A431 和 A549 细胞的细胞毒性。
Phytochemistry. 2010 Sep;71(13):1528-33. doi: 10.1016/j.phytochem.2010.06.008. Epub 2010 Jul 2.
7
A new labdanic norditerpene from Pinus sylvestris.从欧洲赤松中得到的一种新的半日花烷型二萜。
Nat Prod Res. 2010 Oct;24(17):1587-91. doi: 10.1080/14786410802696684.
8
A new diterpenoid and active stilbenes from Pinus armandii heartwood.来自华山松心材的一种新二萜类化合物和活性芪类化合物。
J Asian Nat Prod Res. 2005 Jun;7(3):259-64. doi: 10.1080/10286020410001690163.
9
Pumilol, a Diterpenoid with a Rare Strobane Skeleton from Pinus pumila (Pinaceae).矮松素,一种来自偃松(松科)的具有罕见的松节烷骨架的二萜类化合物。
Chem Biodivers. 2018 Oct;15(10):e1800056. doi: 10.1002/cbdv.201800056. Epub 2018 Sep 3.
10
Antibiotic resistance in Propionibacterium acnes. Microbiological and clinical aspects.痤疮丙酸杆菌中的抗生素耐药性。微生物学和临床方面。
Anaerobe. 2006 Oct-Dec;12(5-6):207-10. doi: 10.1016/j.anaerobe.2006.08.001. Epub 2006 Sep 26.

引用本文的文献

1
Phytochemicals, promising strategies combating .植物化学物质,对抗……的有前景策略 (原文表述不完整)
Front Pharmacol. 2024 Dec 9;15:1476670. doi: 10.3389/fphar.2024.1476670. eCollection 2024.
2
Antiviral Activities of Compounds Isolated from (Pine Tree) against the Influenza A Virus.从(松树)中分离得到的化合物对甲型流感病毒的抗病毒活性。
Biomolecules. 2020 May 4;10(5):711. doi: 10.3390/biom10050711.
3
Bio-Guided Isolation of Methanol-Soluble Metabolites of Common Spruce (Picea abies) Bark by-Products and Investigation of Their Dermo-Cosmetic Properties.
云杉(欧洲云杉)树皮副产物甲醇可溶代谢物的生物导向分离及其皮肤美容特性研究。
Molecules. 2016 Nov 21;21(11):1586. doi: 10.3390/molecules21111586.
4
Diterpenoids from the buds of Pinus banksiana Lamb.来自白皮松芽的二萜。
Molecules. 2012 Aug 13;17(8):9716-27. doi: 10.3390/molecules17089716.
5
Communic acids: occurrence, properties and use as chirons for the synthesis of bioactive compounds.手性酸:作为生物活性化合物合成的手性试剂的存在、性质和用途。
Molecules. 2012 Feb 6;17(2):1448-67. doi: 10.3390/molecules17021448.