Casjens Sherwood R
Department of Pathology, Room 5200K EEJMRB, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Res Microbiol. 2008 Jun;159(5):340-8. doi: 10.1016/j.resmic.2008.04.005. Epub 2008 Apr 30.
Complete genome sequences have been determined for 73 tailed-phages that infect members of the bacterial Enterobacteriaceae family. Biological criteria such as genome size, gene organization and gene orientation were used to place these phages into categories. There are 13 such categories, some of which are themselves extremely diverse. The relationships between and within these categories are discussed with an emphasis on the head assembly genes. Although some of them are clearly homologues, suggesting a very ancient origin, there is little evidence for exchange of individual head genes between these phage categories. More recent horizontal exchange of phage tail fiber and early proteins between the categories occurs, but is probably not extremely rapid.
已测定了73种感染肠杆菌科细菌成员的有尾噬菌体的完整基因组序列。利用基因组大小、基因组织和基因方向等生物学标准将这些噬菌体分类。共有13个这样的类别，其中一些类别本身极其多样。本文讨论了这些类别之间以及类别内部的关系，重点是头部组装基因。尽管其中一些基因显然是同源的，表明起源非常古老，但几乎没有证据表明这些噬菌体类别之间存在单个头部基因的交换。这些类别之间最近发生了噬菌体尾丝和早期蛋白的水平交换，但可能不是非常迅速。
