Parsons J Kellogg, Bergstrom Jaclyn, Silberstein Jonathan, Barrett-Connor Elizabeth
Division of Urology, University of California, San Diego, Medical Center, San Diego, California 92103-8897, USA.
Urology. 2008 Aug;72(2):318-21. doi: 10.1016/j.urology.2008.03.057. Epub 2008 Jun 12.
We analyzed the prevalence and characteristics of lower urinary tract symptoms (LUTS) in community-dwelling men aged 80 years and older.
We administered the American Urological Association Symptom Index (AUA-SI) by mail to 291 surviving community-dwelling male participants in the Rancho Bernardo Study, a prospective, community-based study of aging. We compared the prevalence, severity, and types of LUTS occurring in men who were > or = 80 years to those < 80 years.
The mean age was 74.6 years (standard deviation [SD] 8.9, range 48.3-97.1). One third of the respondents were > or = 80 years. The mean total AUA-SI score increased steadily by decade of life (P-trend = .002). The prevalence of LUTS was 70% in men > or = 80 years and 56% in men < 80 years (P = .03). Men > or = 80 years had significantly higher mean total AUA-SI (P = .05) and were more likely to complain of incomplete emptying (odds ratio [OR] 2.12, 95% confidence interval [CI] 1.06-4.18, P = .02), frequency (OR 1.83, 95% CI 1.00-3.31, P = .03), urgency (OR 1.76, 95% CI 0.96-3.20, P = .05), and weak stream (OR 1.78, 95% CI 1.01-3.12, P = .03).
In this cohort of community-dwelling men, prevalence and severity of LUTS increased into the 10th decade of life. Compared to younger men, men > or = 80 years were more likely to complain of incomplete emptying, frequency, urgency, and weak stream. Further studies of LUTS in older men are needed to better delineate these associations.
我们分析了80岁及以上社区居住男性下尿路症状(LUTS)的患病率及特征。
我们通过邮寄方式向兰乔贝纳多研究中291名存活的社区居住男性参与者发放美国泌尿外科学会症状指数(AUA-SI),该研究是一项基于社区的前瞻性衰老研究。我们比较了80岁及以上男性与80岁以下男性LUTS的患病率、严重程度及类型。
平均年龄为74.6岁(标准差[SD]8.9,范围48.3 - 97.1)。三分之一的受访者年龄在80岁及以上。AUA-SI总分平均每十年稳步上升(P趋势 = 0.002)。80岁及以上男性LUTS的患病率为70%,80岁以下男性为56%(P = 0.03)。80岁及以上男性的AUA-SI总分均值显著更高(P = 0.05),且更有可能主诉排尿不尽(优势比[OR]2.12,95%置信区间[CI]1.06 - 4.18,P = 0.02)、尿频(OR 1.83,95%CI 1.00 - 3.31,P = 0.03)、尿急(OR 1.76,95%CI 0.96 - 3.20,P = 0.05)和尿流无力(OR 1.78,95%CI 1.01 - 3.12,P = 0.03)。
在这一社区居住男性队列中,LUTS的患病率和严重程度在生命的第十个十年有所增加。与年轻男性相比,80岁及以上男性更有可能主诉排尿不尽、尿频、尿急和尿流无力。需要对老年男性的LUTS进行进一步研究,以更好地描述这些关联。