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80岁及以上男性下尿路症状的患病率及特征

Prevalence and characteristics of lower urinary tract symptoms in men aged > or = 80 years.

作者信息

Parsons J Kellogg, Bergstrom Jaclyn, Silberstein Jonathan, Barrett-Connor Elizabeth

机构信息

Division of Urology, University of California, San Diego, Medical Center, San Diego, California 92103-8897, USA.

出版信息

Urology. 2008 Aug;72(2):318-21. doi: 10.1016/j.urology.2008.03.057. Epub 2008 Jun 12.

Abstract

OBJECTIVES

We analyzed the prevalence and characteristics of lower urinary tract symptoms (LUTS) in community-dwelling men aged 80 years and older.

METHODS

We administered the American Urological Association Symptom Index (AUA-SI) by mail to 291 surviving community-dwelling male participants in the Rancho Bernardo Study, a prospective, community-based study of aging. We compared the prevalence, severity, and types of LUTS occurring in men who were > or = 80 years to those < 80 years.

RESULTS

The mean age was 74.6 years (standard deviation [SD] 8.9, range 48.3-97.1). One third of the respondents were > or = 80 years. The mean total AUA-SI score increased steadily by decade of life (P-trend = .002). The prevalence of LUTS was 70% in men > or = 80 years and 56% in men < 80 years (P = .03). Men > or = 80 years had significantly higher mean total AUA-SI (P = .05) and were more likely to complain of incomplete emptying (odds ratio [OR] 2.12, 95% confidence interval [CI] 1.06-4.18, P = .02), frequency (OR 1.83, 95% CI 1.00-3.31, P = .03), urgency (OR 1.76, 95% CI 0.96-3.20, P = .05), and weak stream (OR 1.78, 95% CI 1.01-3.12, P = .03).

CONCLUSIONS

In this cohort of community-dwelling men, prevalence and severity of LUTS increased into the 10th decade of life. Compared to younger men, men > or = 80 years were more likely to complain of incomplete emptying, frequency, urgency, and weak stream. Further studies of LUTS in older men are needed to better delineate these associations.

摘要

目的

我们分析了80岁及以上社区居住男性下尿路症状(LUTS)的患病率及特征。

方法

我们通过邮寄方式向兰乔贝纳多研究中291名存活的社区居住男性参与者发放美国泌尿外科学会症状指数(AUA-SI),该研究是一项基于社区的前瞻性衰老研究。我们比较了80岁及以上男性与80岁以下男性LUTS的患病率、严重程度及类型。

结果

平均年龄为74.6岁(标准差[SD]8.9,范围48.3 - 97.1)。三分之一的受访者年龄在80岁及以上。AUA-SI总分平均每十年稳步上升(P趋势 = 0.002)。80岁及以上男性LUTS的患病率为70%,80岁以下男性为56%(P = 0.03)。80岁及以上男性的AUA-SI总分均值显著更高(P = 0.05),且更有可能主诉排尿不尽(优势比[OR]2.12,95%置信区间[CI]1.06 - 4.18,P = 0.02)、尿频(OR 1.83,95%CI 1.00 - 3.31,P = 0.03)、尿急(OR 1.76,95%CI 0.96 - 3.20,P = 0.05)和尿流无力(OR 1.78,95%CI 1.01 - 3.12,P = 0.03)。

结论

在这一社区居住男性队列中,LUTS的患病率和严重程度在生命的第十个十年有所增加。与年轻男性相比,80岁及以上男性更有可能主诉排尿不尽、尿频、尿急和尿流无力。需要对老年男性的LUTS进行进一步研究,以更好地描述这些关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a64/2597492/860c1bd5b660/nihms64307f1.jpg

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