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基于医院的持续性腹泻前瞻性研究。

Prospective hospital based study on persistent diarrhoea.

作者信息

Dutta P, Lahiri M, Sen D, Pal S C

机构信息

Department of Clinical Medicine, National Institute of Cholera and Enteric Diseases, Calcutta, India.

出版信息

Gut. 1991 Jul;32(7):787-90. doi: 10.1136/gut.32.7.787.

Abstract

A total of 383 children aged less than 5 years suffering from acute watery diarrhoea or dysentery were studied in hospital to determine the rate of persistent diarrhoea. Altogether 335 (87.5%) recovered within 13 days. Only in 48 (12.5%) did the diarrhoea continue for 14 days or more, and they were considered as having persistent diarrhoea. Children aged between 7 and 18 months had a significantly increased incidence of persistent diarrhoea. Children suffering from grade II-IV malnutrition constituted the majority (70.8%) of those with persistent diarrhoea. Higher rates of isolation of Shigella flexneri, Shigella dysenteriae 1, and Salmonella typhimurium were observed among patients with persistent diarrhoea than in those with diarrhoea of shorter duration. No positive correlations were observed between the clinical severity of disease at hospital admission and measles. Breast fed babies were not prone to persistent diarrhoea.

摘要

对383名5岁以下患有急性水样腹泻或痢疾的儿童进行了住院研究,以确定持续性腹泻的发生率。共有335名(87.5%)儿童在13天内康复。只有48名(12.5%)儿童腹泻持续了14天或更长时间,他们被视为患有持续性腹泻。7至18个月大的儿童持续性腹泻的发生率显著增加。患有II-IV级营养不良的儿童占持续性腹泻儿童的大多数(70.8%)。与腹泻持续时间较短的患者相比,持续性腹泻患者中福氏志贺菌、痢疾志贺菌1型和鼠伤寒沙门氏菌的分离率更高。入院时疾病的临床严重程度与麻疹之间未观察到正相关。母乳喂养的婴儿不易患持续性腹泻。

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本文引用的文献

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Jejunal mucosa in infant malnutrition.婴儿营养不良时的空肠黏膜
Am J Clin Nutr. 1968 Sep;21(9):976-83. doi: 10.1093/ajcn/21.9.976.
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