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禽成髓细胞增多症病毒(AMV):只是问题的一个方面。

Avian myeoloblastosis virus (AMV): only one side of the coin.

作者信息

Perbal Bernard

机构信息

Department of Dermatology, University of Michigan Medical School, 1150 W, Medical Center Dr,, Medical Science I, Room 6447, Ann Arbor, Michigan 48109-0609, USA.

出版信息

Retrovirology. 2008 Jun 16;5:49. doi: 10.1186/1742-4690-5-49.

DOI:10.1186/1742-4690-5-49
PMID:18558010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2442608/
Abstract

For many years, scientists and suppliers have refered to AMV-RT as the reverse transcriptase produced by the Avian Myelobalstosis Virus. This manuscript briefly reviews the molecular basis for biological dependence of AMV for the envelope and RT proteins that are produced by its natural helper the Myeloblastosis Associated Virus (MAV). Because the wide use of the term <> obscures scientific facts, it is worthwhile to clarify this issue for the scientific community, especially for younger scientists who might not be aware of the functional relationships that exist between these two viruses.

摘要

多年来,科学家和供应商一直将AMV-RT称为由禽成髓细胞瘤病毒产生的逆转录酶。本手稿简要回顾了AMV对其天然辅助病毒成髓细胞瘤相关病毒(MAV)产生的包膜和RT蛋白生物学依赖性的分子基础。由于“AMV RT”一词的广泛使用掩盖了科学事实,因此值得为科学界澄清这个问题,特别是对于那些可能不了解这两种病毒之间存在的功能关系的年轻科学家。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753b/2442608/83b6192f31c8/1742-4690-5-49-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753b/2442608/83b6192f31c8/1742-4690-5-49-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753b/2442608/83b6192f31c8/1742-4690-5-49-1.jpg

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本文引用的文献

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Transformation by v-Myb.由v-Myb介导的转化
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