Calin Mihaela Antonina, Parasca S V
National Institute of Research and Development for Optoelectronics, P.O. Box MG-5, 1 Atomistilor Street, 077125, Magurele, Ilfov, Romania.
Lasers Med Sci. 2009 May;24(3):453-60. doi: 10.1007/s10103-008-0588-5. Epub 2008 Jul 12.
Bacteria have an important role in human and animal morbidity, and a great number of them have developed antibiotic resistance. In the past recent years a new way of dealing with this problem has been studied: photodynamic inactivation. This method is based on administration of a photosensitizing substance that fixes itself in the bacterial cell followed by exposure to a light source. In the experiments done by many researchers on photodynamic inactivation of bacteria, both coherent and non-coherent light sources were used. This article is a review of these light sources and of some experimental results obtained by different authors.
细菌在人类和动物发病过程中起着重要作用,并且大量细菌已产生抗生素耐药性。在过去几年中,人们研究了一种处理该问题的新方法:光动力灭活。该方法基于给予一种能固定在细菌细胞内的光敏物质,随后暴露于光源。在许多研究人员进行的细菌光动力灭活实验中,使用了相干光源和非相干光源。本文综述了这些光源以及不同作者获得的一些实验结果。