Cornella C, Brustia M, Lazzarich E, Cofano F, Ceruso A, Barbé M C, Fenoglio R, Cella D, Stratta P
Department of Clinical and Experimental Medicine, Amedeo Avogadro University, Novara, Italy.
Transplant Proc. 2008 Jul-Aug;40(6):1865-6. doi: 10.1016/j.transproceed.2008.05.050.
Kidney transplantation not only drastically improves the life-expectancy of hemodialyzed patients, but it also affords psychological and social advantages with improvements in short- and long-term personal and working lives. Quality of life (QoL) is one of the parameters of psychological well-being. There is an improvement of QoL from pre- to posttransplant, but it is not to the level of healthy samples. The aim of this study was to examine QoL in older renal transplant recipients. All recipients older than age 60 were included, with a minimum follow-up of 12 months. To measure QoL, the nationally standardized ShortForm-36 (SF-36) questionnaire was administered. The SF-36 responses by our patients were compared with national age- and gender-appropriate norms, and also between genders. The enrolled population included 19 women (36.5%) and 33 men (63.5%), with a mean age of 66.8 years (range, 60-73 years). Enrolled women reported significant limitations compared to gender- and age-matched norms in social activities (42.11 vs 70.58), perception of pain (22.11 vs 59.17), and general health perception (39.58 vs 48.69). Enrolled men reported significant limitations compared to gender- and age-matched norms in social activities (46.59 vs 78.35), perception of pain (18.18 vs 73.62), psycho-physical energy (50.15 vs 67.88), and general health perception (37.33 vs 61.66). No significant differences were noted between the genders. This study clearly showed how the psychological state was not as good as the clinico-physical recovery following renal transplantation in older recipients.
肾移植不仅能显著提高接受血液透析患者的预期寿命，还能带来心理和社会方面的益处，改善患者短期和长期的个人生活及工作生活。生活质量（QoL）是心理健康的参数之一。从移植前到移植后，患者的生活质量有所改善，但未达到健康样本的水平。本研究的目的是调查老年肾移植受者的生活质量。纳入所有年龄超过60岁的受者，最低随访时间为12个月。为了测量生活质量，采用了全国标准化的简短健康调查问卷（SF - 36）。将我们患者的SF - 36问卷回答与全国年龄和性别匹配的标准进行比较，同时也在不同性别之间进行比较。纳入的人群包括19名女性（36.5%）和33名男性（63.5%），平均年龄为66.8岁（范围为60 - 73岁）。与性别和年龄匹配的标准相比，纳入的女性在社会活动（42.11对70.58）、疼痛感知（22.11对59.17）和总体健康感知（39.58对48.69）方面报告有显著限制。与性别和年龄匹配的标准相比，纳入的男性在社会活动（46.59对78.35）、疼痛感知（18.18对73.62）、心理 - 身体活力（50.15对67.88）和总体健康感知（37.33对61.66）方面报告有显著限制。不同性别之间未发现显著差异。这项研究清楚地表明，老年肾移植受者移植后的心理状态不如临床身体恢复情况良好。
