Spezi Emiliano, Angelini Anna Lisa, Romani Fabrizio, Guido Alessandra, Bunkheila Feisal, Ntreta Maria, Ferri Andrea
Servizio di Fisica Sanitaria, Policlinico S. Orsola Malpighi, Bologna, Italy.
Radiother Oncol. 2008 Oct;89(1):114-22. doi: 10.1016/j.radonc.2008.06.011. Epub 2008 Aug 7.
To investigate the impact of a commercial IMRT/IGRT carbon-fibre tabletop in radiotherapy planning optimization and clinical dose distribution.
In this investigation the Siemens IGRT carbon fibre tabletop, routinely used for IMRT treatments in our Centre, has been incorporated into the CT volume of 6 IMRT patients. This was done by CT scanning the tabletop and by adding the obtained volume to the clinical dataset, acquired using the standard couch available in our CT scanner. This procedure was tested and validated for the purpose of this study. The radiotherapy plans have been optimized using both the original CT volume and the modified CT volume.
IMRT optimization with the tabletop included in the clinical volume produced significantly different deliverable plans compared to standard optimized plans which did not include the treatment couch. Differences up to 6%/7% in terms of total number of MU were found in half of the clinical cases. Differences up to 37% in the number of MU per beam were also found. The number of iterations needed to reach an optimal solution also varied between -18% and +25%. Although the DVH analysis produced similar results, due to the fulfilment of the optimization objectives, differences higher than 10% were found in the dose calculated to superficial regions of the body.
The results of this investigation show that the presence of the carbon fibre tabletop significantly affects the outcome of the beam parameters optimization. We suggest including carbon fibre tabletops into patient treatment planning dose calculation and optimization.
探讨商用调强放疗/图像引导放疗碳纤维治疗床面在放射治疗计划优化及临床剂量分布中的影响。
在本研究中,将我院中心常规用于调强放疗治疗的西门子图像引导放疗碳纤维治疗床面纳入6例调强放疗患者的CT容积中。具体做法是对治疗床面进行CT扫描,并将所得容积添加到临床数据集,该临床数据集是使用我院CT扫描仪配备的标准治疗床获取的。为了本研究的目的,对该程序进行了测试和验证。分别使用原始CT容积和修改后的CT容积对放射治疗计划进行了优化。
与不包括治疗床的标准优化计划相比,临床容积中包含治疗床面的调强放疗优化产生了显著不同的可交付计划。在一半的临床病例中,发现总监测单位数差异高达6%/7%。每束射线的监测单位数差异也高达37%。达到最优解所需的迭代次数也在-18%至+25%之间变化。尽管剂量体积直方图分析产生了相似的结果,由于优化目标的实现,在计算的身体浅表区域剂量中发现差异高于10%。
本研究结果表明,碳纤维治疗床面的存在显著影响射束参数优化的结果。我们建议在患者治疗计划剂量计算和优化中纳入碳纤维治疗床面。