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印度南部40岁以上人群中视网膜色素变性的患病率。

Prevalence of retinitis pigmentosa in South Indian population aged above 40 years.

作者信息

Sen Parveen, Bhargava Arun, George Ronnie, Ve Ramesh S, Hemamalini Arvind, Prema Raju, Kumaramanickavel Govindasamy, Vijaya Lingam

机构信息

Bhagwan Mahavir Vitreo-Retinal Services, Medical Research Foundation, Chennai, Tamil Nadu, India.

出版信息

Ophthalmic Epidemiol. 2008 Jul-Aug;15(4):279-81. doi: 10.1080/09286580802105814.

Abstract

PURPOSE

The study was undertaken to evaluate the prevalence of retinitis pigmentosa (RP) in rural and urban South India.

METHODS

Seven thousand seven hundred and seventy four subjects aged 40 years or more from rural and urban Tamil Nadu, underwent comprehensive ophthalmic examination out of 9576 enumerated (81.17%). After a thorough ophthalmic examination, fundus photographs were taken for documentation. Statistical analysis was done using SPSS for Windows (ver 14).

RESULTS

7461 (95.9%) subjects had fundus details seen in both eyes. Thirteen subjects (0.17%; 4 males, 9 females) were diagnosed as retinitis pigmentosa. Retinitis pigmentosa in the urban population was seen in approximately 1 in 930 persons, while 1 in 372 of rural subjects had the disorder. This figure is greater than other reports from the western populations and that of the conservative estimate of 1 in 4000. The age and gender adjusted prevalence rate of retinitis pigmentosa to national census 2001 was 0.155%. Eight subjects (61.53%) had visual acuity less than 3/60.

CONCLUSION

Prevalence of RP in South India appears to be alarmingly higher in comparison to those seen in other parts of the world.

摘要

目的

本研究旨在评估印度南部城乡地区视网膜色素变性(RP)的患病率。

方法

在泰米尔纳德邦城乡地区9576名登记在册的40岁及以上受试者中,7774名(81.17%)接受了全面眼科检查。经过全面眼科检查后,拍摄眼底照片用于记录。使用Windows版SPSS(版本14)进行统计分析。

结果

7461名(95.9%)受试者双眼眼底情况清晰可见。13名受试者(0.17%;4名男性,9名女性)被诊断为视网膜色素变性。城市人口中视网膜色素变性的患病率约为每930人中有1例,而农村受试者中每372人中有1例患有该疾病。这一数字高于西方人群的其他报告以及保守估计的每4000人中有1例。根据2001年全国人口普查调整后的视网膜色素变性年龄和性别患病率为0.155%。8名受试者(61.53%)视力低于3/60。

结论

与世界其他地区相比,印度南部视网膜色素变性的患病率似乎高得惊人。

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