体外爱泼斯坦-巴尔病毒DNA的合成：膦甲酸、N-乙基马来酰亚胺和ATP的作用。
Synthesis of Epstein-Barr virus DNA in vitro: effects of phosphonoacetic acid, N-ethylmaleimide, and ATP.
作者信息
Seebeck T, Shaw J E, Pagano J S
出版信息
J Virol. 1977 Jan;21(1):435-8. doi: 10.1128/JVI.21.1.435-438.1977.
Abstract
Nuclei from superinfected Raji cells synthesized Epstein-Barr Virus (EBV) DNA in vitro in the absence of cell DNA synthesis. The synthesis of EBV DNA in vitro was inhibited by phosphonoacetic acid and N-ethylmaleimide, and maximum synthesis was achieved in the absence of an ATP-regenerating system. Nuclei from mock-infected cells required an ATP-regenerating system for maximum DNA synthesis.
摘要
来自超感染拉吉细胞的细胞核在无细胞DNA合成的情况下于体外合成了爱泼斯坦-巴尔病毒（EBV）DNA。体外EBV DNA的合成受到膦甲酸和N-乙基马来酰亚胺的抑制，并且在没有ATP再生系统的情况下实现了最大合成。来自模拟感染细胞的细胞核需要ATP再生系统来实现最大DNA合成。
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