妊娠期弓形虫病：一例病例报告及文献综述
Toxoplasmosis during pregnancy: a case report and review of the literature.
作者信息
Giannoulis C, Zournatzi B, Giomisi A, Diza E, Tzafettas I
机构信息
2nd Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Greece.
出版信息
Hippokratia. 2008 Jul;12(3):139-43.
Although toxoplasmosis is considered harmless for a non-pregnant woman, it is potentially harmful during pregnancy, especially at first trimester. The aim of this study is to increase our alertness and monitoring in case of toxoplasmosis during pregnancy, given that when diagnosed it can be effectively treated.We present a case of a healthy 26 years old adult woman, found with toxoplasmosis during the 13th week of pregnancy. The role of frequent maternal and fetus immunological tests, PCR-tests of the amniotic fluid and ultrasound screening of the fetus throughout pregnancy was of great value. The patient was treated with spiramycin (1 grx3) from the 16th week of pregnancy. The patient was subjected to cesarean delivery at the 36th week of pregnancy due to preterm contractions and history of previous cesarean delivery. The newborn was a healthy girl with a birth weight of 2880 gr. A two-year follow up of the baby revealed no medical condition. Maternal infections are a serious medical condition during pregnancy. Toxoplasmosis when diagnosed on time and treated properly can lead to healthy offspring.
虽然弓形虫病对非孕妇被认为是无害的，但在怀孕期间，尤其是孕早期，它可能是有害的。鉴于弓形虫病在被诊断出时可以得到有效治疗，本研究的目的是提高我们在孕期弓形虫病情况下的警觉性和监测。我们报告一例健康的26岁成年女性病例，她在怀孕第13周时被发现患有弓形虫病。在整个孕期频繁进行母体和胎儿免疫学检测、羊水PCR检测以及胎儿超声筛查起到了很大的作用。该患者从怀孕第16周开始接受螺旋霉素治疗（1克×3次）。由于早产宫缩和既往剖宫产史，患者在怀孕第36周时接受了剖宫产。新生儿是一名健康女婴，出生体重2880克。对婴儿进行的两年随访显示没有健康问题。孕期母体感染是一种严重的病症。弓形虫病如果及时诊断并正确治疗，可以生出健康的后代。
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