Ojo Olabisi, Sheehan Stella, Corcoran G Daniel, Okker Melissa, Gover Karen, Nikolayevsky Vladyslav, Brown Timothy, Dale James, Gordon Stephen V, Drobniewski Francis, Prentice Michael B
University College Cork, Cork, Ireland.
Emerg Infect Dis. 2008 Dec;14(12):1931-4. doi: 10.3201/eid1412.071135.
Mycobacterium bovis caused 3% of human tuberculosis cases in southwest Ireland during 1998-2006. Of 11 M. bovis strains genotyped, 9 belonged to common animal spoligotypes. Seven strains were from sputum and potential sources of human-centered disease transmission. Ten-locus variable-number tandem repeat typing gave unique strain profiles and would detect disease outbreaks.
1998年至2006年期间,牛分枝杆菌导致爱尔兰西南部3%的人类结核病病例。在11株进行基因分型的牛分枝杆菌菌株中,9株属于常见的动物间隔寡核苷酸分型。7株来自痰液以及可能的以人为中心的疾病传播源。十位点可变数目串联重复序列分型给出了独特的菌株图谱,可用于检测疾病暴发。