Mignard Sophie, Pichat Catherine, Carret Gerard
Laboratoire de bacteriologie, Centre Hospitalier Lyon Sud, Lyon, France.
Emerg Infect Dis. 2006 Sep;12(9):1431-3. doi: 10.3201/eid1209.060209.
In a 5-year retrospective study, we used spoligotyping and mycobacterial interspersed repetitive units to type 13 strains of Mycobacterium bovis isolated from human sources. Despite the relatively high incidence of human tuberculosis caused by M. bovis (2%), these tools showed no clonal evolution and no relationships between the isolates.
在一项为期5年的回顾性研究中,我们使用间隔寡核苷酸分型(spoligotyping)和分枝杆菌散布重复单位对从人类样本中分离出的13株牛分枝杆菌菌株进行分型。尽管牛分枝杆菌引起的人类结核病发病率相对较高(2%),但这些工具并未显示出克隆进化以及分离株之间的关联。