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基于伞形酮荧光团的荧光过氧化氢探针的合理设计。

Rational Design of a Fluorescent Hydrogen Peroxide Probe Based on the Umbelliferone Fluorophore.

作者信息

Du Lupei, Li Minyong, Zheng Shilong, Wang Binghe

机构信息

Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, GA 30302-4098, USA.

出版信息

Tetrahedron Lett. 2008 May 5;49(19):3045-3048. doi: 10.1016/j.tetlet.2008.03.063.

DOI:10.1016/j.tetlet.2008.03.063
PMID:19081820
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2490821/
Abstract

In this study, we report a novel water-soluble umbelliferone-based fluorescent probe for hydrogen peroxide. This probe shows very large increases (up to 100 fold) in fluorescent intensity upon reaction with hydrogen peroxide, and good selectivity over other reactive oxygen species (ROS).

摘要

在本研究中,我们报道了一种新型的基于伞形酮的水溶性过氧化氢荧光探针。该探针与过氧化氢反应后荧光强度大幅增加(高达100倍),并且对其他活性氧(ROS)具有良好的选择性。

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