Al-Turki Haifa A, Sadat-Ali Mir, Al-Elq Abdulmohsen H, Al-Mulhim Fathma A, Al-Ali Amein K
Department of Obstetrics and Gynecology, College of Medicine, King Faisal University, Dammam and King Fahd University Hospital, Al-Khobar, Kingdom of Saudi Arabia.
Saudi Med J. 2008 Dec;29(12):1765-8.
To assess the serum level of 25 hydroxyvitamin D 25OHD among healthy Saudi Arabian women living in the eastern province.
A cross-sectional randomized study was conducted between February 1st 2008 and May 31st 2008 at the King Fahd University Hospital, Al-Khobar, Kingdom of Saudi Arabia in 200 Saudi women between 25-35 years group 1 and women of > or =50 years group 2. Clinical examination, laboratory tests, a complete blood picture, serum calcium, phosphorous, alkaline phosphatase, parathormone, and the serum levels of 25OHD levels were carried out. Data on lifestyle, dietary, and demographic questionnaires were collected. Vitamin D was defined as deficient with serum level <50 nmol/L, insufficient between 52-72 nmol/L, and normal as 75nmol/L.
In group 1, 70% of women had normal 25OHD, and in women of group 2, 45% had normal levels of 25OHD. Alkaline phosphatase and parathormone levels were significantly higher in women with low vitamin D levels. Sun exposure and consumption of dairy products were minimal.
Vitamin D deficiency among healthy young Saudi women of 25-35 years was 30% and 55% in women of > or =50 years. This study indicates that hypovitaminosis D is common in young and postmenopausal women. Efforts are require to augment and encouraged women for adequate exposure to sunlight and increased intake of fortified vitamin D products to maintain skeletal health.
评估生活在沙特阿拉伯东部省份的健康沙特女性血清中25-羟维生素D（25OHD）的水平。
2008年2月1日至2008年5月31日在沙特阿拉伯王国胡拜尔市法赫德国王大学医院进行了一项横断面随机研究，研究对象为200名沙特女性，其中25 - 35岁的女性为第1组，50岁及以上的女性为第2组。进行了临床检查、实验室检测、全血细胞计数、血清钙、磷、碱性磷酸酶、甲状旁腺激素以及25OHD水平检测。收集了生活方式、饮食和人口统计学调查问卷的数据。维生素D缺乏定义为血清水平<50 nmol/L，不足为52 - 72 nmol/L，正常为75nmol/L。
在第1组中，70%的女性25OHD水平正常，在第2组女性中，45%的女性25OHD水平正常。维生素D水平低的女性碱性磷酸酶和甲状旁腺激素水平显著更高。日照和乳制品摄入量极少。
25 - 35岁健康沙特年轻女性维生素D缺乏率为30%，50岁及以上女性为55%。本研究表明维生素D缺乏在年轻女性和绝经后女性中很常见。需要努力加强并鼓励女性充分晒太阳，增加强化维生素D产品的摄入量以维持骨骼健康。
