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巴西米纳斯吉拉斯州贝洛奥里藏特市一家公立医院收治的艾滋病患者口腔念珠菌病的发病率及解剖定位

Incidence and anatomic localization of oral candidiasis in patients with AIDS hospitalized in a public hospital in Belo Horizonte, MG, Brazil.

作者信息

Gabler Ilanna G, Barbosa Anne C, Velela Raquel R, Lyon Sandra, Rosa Carlos A

机构信息

Department of Microbiology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.

出版信息

J Appl Oral Sci. 2008 Jul-Aug;16(4):247-50. doi: 10.1590/s1678-77572008000400004.

Abstract

The objective of this study was to evaluate the incidence, anatomic localization and yeast species isolated from each clinical type of oral candidiasis. The clinical samples were obtained from 67 patients with AIDS with CD4 cell counts below 200 cells/mm(3) and hospitalized in a public hospital (Eduardo de Menezes Hospital) in the city of Belo Horizonte, MG, Brazil. Yeasts were isolated using Chromagar Candida. The results show that 50.7% of these patients had oral candidiasis. The pseudomembranous form was the most frequent clinical manifestation of oral candidiasis, followed by the erythematous and angular cheilite forms. The most common site of these clinical forms of oral candidiasis was the tongue. Candida albicans was the most common yeast species isolated from the lesions. However, other species were also found to be associated with these forms of oral candidiasis.

摘要

本研究的目的是评估从每种临床类型的口腔念珠菌病中分离出的酵母菌的发病率、解剖定位及菌种。临床样本取自67例艾滋病患者,其CD4细胞计数低于200个细胞/mm³,均在巴西米纳斯吉拉斯州贝洛奥里藏特市的一家公立医院(爱德华多·德·梅内塞斯医院)住院。使用科玛嘉念珠菌显色培养基分离酵母菌。结果显示,这些患者中有50.7%患有口腔念珠菌病。假膜型是口腔念珠菌病最常见的临床表现,其次是红斑型和口角炎型。这些临床类型的口腔念珠菌病最常见的部位是舌头。白色念珠菌是从病变部位分离出的最常见的酵母菌菌种。然而,也发现其他菌种与这些类型的口腔念珠菌病有关。

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本文引用的文献

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Fungal infections in primary immunodeficiencies.原发性免疫缺陷中的真菌感染
Eur J Pediatr. 2007 Nov;166(11):1099-117. doi: 10.1007/s00431-007-0527-7. Epub 2007 Jun 6.
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Oral manifestations in HIV/AIDS infected patients from India.印度HIV/AIDS感染患者的口腔表现。
Oral Dis. 2006 Nov;12(6):537-42. doi: 10.1111/j.1601-0825.2006.01232.x.
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Oral manifestation of HIV/AIDS in Plateau state indigenes, Nigeria.
West Afr J Med. 2006 Jan-Mar;25(1):32-7. doi: 10.4314/wajm.v25i1.28242.

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