Dorshkind Kenneth, Montecino-Rodriguez Encarnacion, Signer Robert A J
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California 90095, USA.
Nat Rev Immunol. 2009 Jan;9(1):57-62. doi: 10.1038/nri2471.
Ageing is accompanied by a decline in the function of the immune system, which increases susceptibility to infections and can decrease the quality of life. The ability to rejuvenate the ageing immune system would therefore be beneficial for elderly individuals and would decrease health-care costs for society. But is the immune system ever too old to become young again? We review here the promise of various approaches to rejuvenate the function of the immune system in the rapidly growing ageing population.
衰老伴随着免疫系统功能的衰退，这会增加感染易感性并可能降低生活质量。因此，恢复衰老免疫系统的功能对老年人有益，并会降低社会的医疗保健成本。但是，免疫系统是否会老到无法再恢复年轻呢？我们在此回顾在迅速增长的老年人群体中恢复免疫系统功能的各种方法所带来的希望。
