Liu Youfang, Athanasiadis Georgios, Weale Michael E
Bioinformatics Research Center, North Carolina State University, Raleigh, NC 27695-7566, USA.
Hum Genomics. 2008 Sep;3(1):79-86. doi: 10.1186/1479-7364-3-1-79.
A number of programs have been developed for simulating population genetic and genetic epidemiological data conforming to one of three main algorithmic approaches: 'forwards', 'backwards' and 'sideways'. This review aims to make the reader aware of the range of options currently available to them. While no one program emerges as the best choice in all circumstances, we nominate a set of those which currently appear most promising.
已经开发了许多程序，用于模拟符合三种主要算法方法之一的群体遗传和遗传流行病学数据：“正向”、“反向”和“侧向”。本综述旨在让读者了解他们目前可用的选择范围。虽然没有一个程序在所有情况下都是最佳选择，但我们推荐一组目前看起来最有前景的程序。
